Abstract
Sixteen normal individuals and 100 hospital patients, all black, were tested for abnormal carcinoembryonic antigen (CEA) levels. Male and female subjects (smokers and non-smokers) were tested. The results of the tests are discussed. For normal subjects, the CEA values ranged from 0.0 ng/ml to 2.6 ng/ml. Among hospital patients with neoplastic disease, male patients with lung disease showed elevated CEA titers but their female counterparts did not. On the other hand, female patients with breast cancer, in contrast to their male counterparts, had raised values of CEA. The clinical indices for laboratory tests of sensitivity, specificity, and predictive value were calculated and determined to be 71.5, 56, and 47.5 percent, respectively.
Full text
PDF





Selected References
These references are in PubMed. This may not be the complete list of references from this article.
- Chu T. M. Current status of carcinoembryonic antigen assay. Semin Nucl Med. 1975 Jul;5(3):255–262. doi: 10.1016/s0001-2998(75)80013-4. [DOI] [PubMed] [Google Scholar]
- Frost M. A., Coates A. S. Plasma carcinoembryonic antigen in an Australian hospital population. Med J Aust. 1976 Jun 19;1(25):950–953. [PubMed] [Google Scholar]
- Gardner R. C., Feinerman A. E., Kantrowitz P. A., Gottblatt S., Loewenstein M. S., Zamcheck N. Serial carcinoembryonic antigen (CEA) blood levels in patients with ulcerative colitis. Am J Dig Dis. 1978 Feb;23(2):129–133. doi: 10.1007/BF01073187. [DOI] [PubMed] [Google Scholar]
- Gold P., Freedman S. O. Specific carcinoembryonic antigens of the human digestive system. J Exp Med. 1965 Sep 1;122(3):467–481. doi: 10.1084/jem.122.3.467. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Hansen H. J., Snyder J. J., Miller E., Vandevoorde J. P., Miller O. N., Hines L. R., Burns J. J. Carcinoembryonic antigen (CEA) assay. A laboratory adjunct in the diagnosis and management of cancer. Hum Pathol. 1974 Mar;5(2):139–147. doi: 10.1016/s0046-8177(74)80061-4. [DOI] [PubMed] [Google Scholar]
- Moore T. L., Kupchik H. Z., Marcon N., Zamcheck N. Carcinoembryonic antigen assay in cancer of the colon and pancreas and other digestive tract disorders. Am J Dig Dis. 1971 Jan;16(1):1–7. doi: 10.1007/BF02233781. [DOI] [PubMed] [Google Scholar]
- Pick A. I., Shoenfeld Y., Zelikovski A., Wolloch J., Mintz U. Diagnostic significance of carcinoembryonic antigen (CEA) concentrations: --a study of 61 patients with malignancies--. Am J Proctol. 1977 Jun;28(3):37–43. [PubMed] [Google Scholar]
