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. 1955;13(6):937–998.

Synthetic substances with morphine-like effect

Relationship between chemical structure and analgesic action*

Olav J Braenden, Nathan B Eddy, H Halbach
PMCID: PMC2538094  PMID: 13284565

Abstract

For morphine-, morphinan-, pethidine-, methadone-, and dithienyl-butenylamine groups of analgesic compounds a systematic survey is given of how analgesic activity is quantitatively affected by alteration of the chemical constitution. Features common to the structural formulae of substances with morphine-like analgesic effect are pointed out.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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