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. 1957;16(2):295–430.

Cholera studies*

9. Symptomatology, diagnosis, prognosis and treatment

R Pollitzer
PMCID: PMC2538236  PMID: 13426761

Abstract

Discussing the symptomatology of cholera, the author deals first with the incubation period, the clinical types, choleraic diarrhoea, and cholerine; he then considers in detail the various stages of cholera gravis and the relapses and complications that may be met. This is followed by sections on diagnosis and differential diagnosis, and on prognosis and the various factors influencing it. The author's highly detailed review of the treatment of cholera which concludes this study is divided into three parts, dealing with attempts at specific therapy, with infusion treatment, and with adjuvant treatment.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. ABDULLA M., ROHINI D. K. Chemotherapy of cholera with a new sulphone compound. Ind Med Gaz. 1950 May;85(5):202–202. [PMC free article] [PubMed] [Google Scholar]
  2. BHATNAGAR S. S., DE SA J. Chemotherapy of cholera with a new sulphonamide compound (6257) laboratory investigations and field trials. Br Med J. 1948 Apr 17;1(4554):719–723. doi: 10.1136/bmj.1.4554.719. [DOI] [PMC free article] [PubMed] [Google Scholar]
  3. BURROWS W. Studies on immunity to Asiatic cholera. VI. Observations on the relation of antibody to effective immunity to experimental enteric cholera, with a note on sulfonamide therapy. J Infect Dis. 1953 Mar-Apr;92(2):152–163. doi: 10.1093/infdis/92.2.152. [DOI] [PubMed] [Google Scholar]
  4. Brunton T. L. On the Use of Atropine in Cholera. Med Chir Trans. 1893;76:357–373. doi: 10.1177/095952879307600123. [DOI] [PMC free article] [PubMed] [Google Scholar]
  5. CHAKRAVARTI H. S., CHAUDHURI R. N. Plasma sodium, potassium and chloride changes in cholera and their significance in prognosis and treatment. J Indian Med Assoc. 1954 Aug;23(11):488–491. [PubMed] [Google Scholar]
  6. CHAKRAVARTI H. S., MONDAL A., MUKHERJEE A. M., PAL N. G. Further observations on intravenous chloramphenicol in cholera. J Indian Med Assoc. 1954 May;23(8):331–332. [PubMed] [Google Scholar]
  7. CHATTERJEE H. N. Control of vomiting in cholera and oral replacement of fluid. Lancet. 1953 Nov 21;265(6795):1063–1063. doi: 10.1016/s0140-6736(53)90668-0. [DOI] [PubMed] [Google Scholar]
  8. CHAUDHURI R. N., CHAKRAVARTI H., DUTTA B. N. Studies on body-fluid changes in cholera. Indian J Med Res. 1951 Oct;39(4):559–569. [PubMed] [Google Scholar]
  9. CHAUDHURI R. N., GHOSAL S., RAI CHAUDHURI M. N. Chloromycetin in the treatment of cholera. Ind Med Gaz. 1950 Sep;85(9):398–400. [PMC free article] [PubMed] [Google Scholar]
  10. COLLIER H. O. J., HALL I. F., WATERHOUSE P. D. The laboratory evaluation of remedies for cholera. Ann Trop Med Parasitol. 1949 Oct;43(2):155–163. doi: 10.1080/00034983.1949.11685401. [DOI] [PubMed] [Google Scholar]
  11. Cannon A. THE ESSENTIAL OIL TREATMENT OF CHOLERA. Br Med J. 1927 Jan 15;1(3445):98–98. doi: 10.1136/bmj.1.3445.98. [DOI] [PMC free article] [PubMed] [Google Scholar]
  12. DAS A., GHOSAL S., GUPTA S. K., CHAUDHURI R. N. Terramycin in cholera. Ind Med Gaz. 1951 Oct;86(10):437–444. [PMC free article] [PubMed] [Google Scholar]
  13. DAS A., GHOSAL S., GUPTA S. K. Intravenous terramycin in cholera. J Indian Med Assoc. 1953 Apr;22(7):272–273. [PubMed] [Google Scholar]
  14. DAS A., GHOSAL S., MONDAL A., GUPTA S. K. Terramycin in cholera. J Indian Med Assoc. 1953 Apr;22(7):268–271. [PubMed] [Google Scholar]
  15. DE S. N., BHATTACHARYYA K., RAYCHAUDHURY P. K. In-vitro study of the actions of terramycin and chloromycetin against Vibrio cholerae; preliminary report. Calcutta Med J. 1952 Sep;49(9):360–361. [PubMed] [Google Scholar]
  16. DE S. N., SENGUPTA K. P., CHANDA N. N. Intravascular haemolysis in cholera; the effect of oxytetracycline. Lancet. 1954 Apr 17;266(6816):807–809. doi: 10.1016/s0140-6736(54)91477-4. [DOI] [PubMed] [Google Scholar]
  17. DUTTA N. K., HABBU M. K. Experimental cholera in infant rabbits: a method for chemotherapeutic investigation. Br J Pharmacol Chemother. 1955 Jun;10(2):153–159. doi: 10.1111/j.1476-5381.1955.tb00074.x. [DOI] [PMC free article] [PubMed] [Google Scholar]
  18. FELSENFELD O., SOMAN D. W., ISHIHARA S. J., WATERS T., NORSEN J. In vitro sensitivity of recently isolated cholera vibrios to ten antibiotics. Proc Soc Exp Biol Med. 1951 Jun;77(2):287–288. doi: 10.3181/00379727-77-18752. [DOI] [PubMed] [Google Scholar]
  19. FELSENFELD O., SOMAN D. W. Treatment of cholera with antibiotics. Ann N Y Acad Sci. 1952 Dec 30;55(6):1059–1062. doi: 10.1111/j.1749-6632.1952.tb22665.x. [DOI] [PubMed] [Google Scholar]
  20. GHANEM M. H., MIKHAIL M. N. Clinical and biochemical studies in cholera and the rationale of treatment. Trans R Soc Trop Med Hyg. 1949 Jul;43(1):81–96. doi: 10.1016/0035-9203(49)90028-0. [DOI] [PubMed] [Google Scholar]
  21. GOHAR M. A. Sensitivity of the cholera vibrio to antibiotics. J Trop Med Hyg. 1953 Dec;56(12):289–294. [PubMed] [Google Scholar]
  22. Gauld R. L., Schlingman A. S., Jackson E. B., Manning M. C., Batson H. C., Campbell C. C. CHLORAMPHENICOL (CHLOROMYCETIN) IN EXPERIMENTAL CHOLERA INFECTIONS. J Bacteriol. 1949 Mar;57(3):349–352. [PMC free article] [PubMed] [Google Scholar]
  23. Ghosh H. Further Investigation of a New Anti-Cholera Serum. Br Med J. 1936 May 9;1(3931):936–938. doi: 10.1136/bmj.1.3931.936. [DOI] [PMC free article] [PubMed] [Google Scholar]
  24. Ghosh H. TREATMENT OF CHOLERA WITH A NEW ANTI-CHOLERA SERUM: PRELIMINARY NOTE. Br Med J. 1935 Jan 12;1(3862):56–57. doi: 10.1136/bmj.1.3862.56. [DOI] [PMC free article] [PubMed] [Google Scholar]
  25. Hort E. C., Penfold W. J. THE DANGERS OF SALINE INJECTIONS. Br Med J. 1911 Dec 16;2(2659):1589–1591. doi: 10.1136/bmj.2.2659.1589. [DOI] [PMC free article] [PubMed] [Google Scholar]
  26. KONAR N. R., SENGUPTA A. N. Terramycin in cholera. Ind Med Gaz. 1951 Oct;86(10):469–470. [PMC free article] [PubMed] [Google Scholar]
  27. LAHIRI S. C., BASU S. N. L-noradrenalin in the treatment of circulatory collapse in cholera. J Indian Med Assoc. 1954 Apr;23(7):285–288. [PubMed] [Google Scholar]
  28. LAHIRI S. C. Chemotherapy in cholera. Br Med J. 1951 Mar 10;1(4705):500–504. doi: 10.1136/bmj.1.4705.500. [DOI] [PMC free article] [PubMed] [Google Scholar]
  29. LAIGRET J. L'A.C.T.H. dans le traitement du cholera. Med Trop (Mars) 1954 Nov-Dec;14(6):754–757. [PubMed] [Google Scholar]
  30. Lees J. C., Levvy G. A. Emergency Preparation of Pyrogenfree Water. Br Med J. 1940 Mar 16;1(4132):430–432. doi: 10.1136/bmj.1.4132.430. [DOI] [PMC free article] [PubMed] [Google Scholar]
  31. MENON I. G. K. Intestinal fuso-spirochaetosis simulating cholera. Br Med J. 1947 Jun 28;1(4512):948–948. doi: 10.1136/bmj.1.4512.948. [DOI] [PMC free article] [PubMed] [Google Scholar]
  32. NAGAO I. Comparative study of roseomycin, streptomycin, chloramphenicol and homosulfanilamide on the effect of experimental cholera infections. Tohoku J Exp Med. 1953;58(2):191–194. doi: 10.1620/tjem.58.191. [DOI] [PubMed] [Google Scholar]
  33. OLEJNIK E., DAVIDOVITCH S. Action of terramycin and chloromycetin on cholera Vibrio in mice. Nature. 1951 Oct 13;168(4276):654–654. doi: 10.1038/168654a0. [DOI] [PubMed] [Google Scholar]
  34. PANDIT S. R. A note on cholera in Assam and the cholera bacteriophage experiment carried out in Assam. Indian J Med Res. 1951 Apr;39(2):197–210. [PubMed] [Google Scholar]
  35. Rogers L. A SIMPLE CURATIVE TREATMENT OF CHOLERA. Br Med J. 1910 Sep 24;2(2595):835–839. doi: 10.1136/bmj.2.2595.835. [DOI] [PMC free article] [PubMed] [Google Scholar]
  36. SEAL S. C., GHOSAL S. C., GHOSH M. M. A preliminary trial of aureomycin (I.V.) in the treatment of cholera. Ind Med Gaz. 1951 Jul;86(7):287–289. [PMC free article] [PubMed] [Google Scholar]
  37. SEAL S. C., GHOSH M. M., GHOSAL S. C. Further trial of aureomycin in the treatment of cholera. Br Med J. 1954 Mar 27;1(4864):740–742. doi: 10.1136/bmj.1.4864.740. [DOI] [PMC free article] [PubMed] [Google Scholar]
  38. SENECA H., HENDERSON E. Laboratory diagnosis of cholera. Am J Trop Med Hyg. 1949 Nov;29(6):921–924. doi: 10.4269/ajtmh.1949.s1-29.921. [DOI] [PubMed] [Google Scholar]
  39. SENECA H., HENDERSON E. Phthalylsulfacetimide (thalamyd) in cholera. Am J Trop Med Hyg. 1949 May;29(3):425–428. doi: 10.4269/ajtmh.1949.s1-29.425. [DOI] [PubMed] [Google Scholar]
  40. TAO S. C., WOO M. O., LOH W. P. Clinical observations on 687 cases of cholera. Chin Med J. 1948 Jul;66(7):377–386. [PubMed] [Google Scholar]

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