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. 1986 Oct;60(1):286–289. doi: 10.1128/jvi.60.1.286-289.1986

Pathogenicity of herpes simplex virus mutants containing drug resistance mutations in the viral DNA polymerase gene.

H J Field, D M Coen
PMCID: PMC253927  PMID: 3018291

Abstract

Three herpes simplex virus mutants that contain drug resistance mutations in the DNA polymerase gene exhibited no significant reduction in replication in the ears of mice compared with the wild type after inoculation at that site but were attenuated for pathogenicity after intracerebral inoculation. Cataracts were common sequelae in mice that survived mutant infections.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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