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. 1994 Apr 30;308(6937):1132–1135. doi: 10.1136/bmj.308.6937.1132

Childhood eczema: disease of the advantaged?

H C Williams 1, D P Strachan 1, R J Hay 1
PMCID: PMC2540131  PMID: 8173454

Abstract

OBJECTIVE--To determine whether the increased prevalence of childhood eczema in advantaged socioeconomic groups is due to increased parental reporting. DESIGN--Comparison of parental reports of eczema with visible eczema recorded by medical officers during a detailed physical examination. SETTING--National birth cohort study. SUBJECTS--8279 children from England, Wales, and Scotland born during 3-9 March 1958 and followed up at the ages of 7, 11, and 16. MAIN OUTCOME MEASURES--Prevalence of eczema according to parental report compared with medical officer's examination at the ages of 7, 11, and 16. RESULTS--Prevalence of both reported and examined eczema increased with rising social class at the ages of 7, 11, and 16 years. The point prevalence of examined eczema at age 7 was 4.8%, 3.6%, 3.6%, 2.4%, 2.2%, and 2.4% in social classes I, II, III non-manual, III manual, IV, and V respectively (chi 2 value for linear trend 12.6, P < 0.001). This trend persisted after adjustment for potential confounders such as region and family size and was not present for examined psoriasis or acne. CONCLUSIONS--Eczema is more prevalent among British schoolchildren in social classes I and II than those in lower classes. Exposures associated with social class are probably at least as important as genetic factors in the expression of childhood eczema.

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Selected References

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  1. Anderson H. R., Bland J. M., Patel S., Peckham C. The natural history of asthma in childhood. J Epidemiol Community Health. 1986 Jun;40(2):121–129. doi: 10.1136/jech.40.2.121. [DOI] [PMC free article] [PubMed] [Google Scholar]
  2. Arshad S. H., Hide D. W. Effect of environmental factors on the development of allergic disorders in infancy. J Allergy Clin Immunol. 1992 Aug;90(2):235–241. doi: 10.1016/0091-6749(92)90077-f. [DOI] [PubMed] [Google Scholar]
  3. Arshad S. H., Matthews S., Gant C., Hide D. W. Effect of allergen avoidance on development of allergic disorders in infancy. Lancet. 1992 Jun 20;339(8808):1493–1497. doi: 10.1016/0140-6736(92)91260-f. [DOI] [PubMed] [Google Scholar]
  4. Barbee R. A., Lebowitz M. D., Thompson H. C., Burrows B. Immediate skin-test reactivity in a general population sample. Ann Intern Med. 1976 Feb;84(2):129–133. doi: 10.7326/0003-4819-84-2-129. [DOI] [PubMed] [Google Scholar]
  5. Bowker N. C., Cross K. W., Fairburn E. A., Wall M. Sociological implications of an epidemiological study of eczema in the City of Birmingham. Br J Dermatol. 1976 Aug;95(2):137–144. doi: 10.1111/j.1365-2133.1976.tb00816.x. [DOI] [PubMed] [Google Scholar]
  6. Burr M. L., Miskelly F. G., Butland B. K., Merrett T. G., Vaughan-Williams E. Environmental factors and symptoms in infants at high risk of allergy. J Epidemiol Community Health. 1989 Jun;43(2):125–132. doi: 10.1136/jech.43.2.125. [DOI] [PMC free article] [PubMed] [Google Scholar]
  7. FREEMAN G. L., JOHNSON S. ALLERGIC DISEASES IN ADOLESCENTS. I. DESCRIPTION OF SURVEY; PREVALENCE OF ALLERGY. Am J Dis Child. 1964 Jun;107:549–559. doi: 10.1001/archpedi.1964.02080060551001. [DOI] [PubMed] [Google Scholar]
  8. FREEMAN G. L., JOHNSON S. ALLERGIC DISEASES IN ADOLESCENTS. I. DESCRIPTION OF SURVEY; PREVALENCE OF ALLERGY. Am J Dis Child. 1964 Jun;107:549–559. doi: 10.1001/archpedi.1964.02080060551001. [DOI] [PubMed] [Google Scholar]
  9. Forster J., Dungs M., Wais U., Urbanek R. Atopie-verdächtige Symptome in den ersten zwei Lebensjahren. Einfluss von Geburtsreife, Ernährung und Sozialstatus. Klin Padiatr. 1990 May-Jun;202(3):136–140. doi: 10.1055/s-2007-1025506. [DOI] [PubMed] [Google Scholar]
  10. Gergen P. J., Turkeltaub P. C., Kovar M. G. The prevalence of allergic skin test reactivity to eight common aeroallergens in the U.S. population: results from the second National Health and Nutrition Examination Survey. J Allergy Clin Immunol. 1987 Nov;80(5):669–679. doi: 10.1016/0091-6749(87)90286-7. [DOI] [PubMed] [Google Scholar]
  11. Golding J., Peters T. J. The epidemiology of childhood eczema: I. A population based study of associations. Paediatr Perinat Epidemiol. 1987 Apr;1(1):67–79. doi: 10.1111/j.1365-3016.1987.tb00091.x. [DOI] [PubMed] [Google Scholar]
  12. Larsson P. A., Lidén S. Prevalence of skin diseases among adolescents 12--16 years of age. Acta Derm Venereol. 1980;60(5):415–423. [PubMed] [Google Scholar]
  13. Meding B., Swanbeck G. Prevalence of hand eczema in an industrial city. Br J Dermatol. 1987 May;116(5):627–634. doi: 10.1111/j.1365-2133.1987.tb05895.x. [DOI] [PubMed] [Google Scholar]
  14. Peters T. J., Golding J. The epidemiology of childhood eczema: II. Statistical analyses to identify independent early predictors. Paediatr Perinat Epidemiol. 1987 Apr;1(1):80–94. doi: 10.1111/j.1365-3016.1987.tb00092.x. [DOI] [PubMed] [Google Scholar]
  15. Rajka G. Atopic dermatitis. Correlation of environmental factors with frequency. Int J Dermatol. 1986 Jun;25(5):301–304. doi: 10.1111/j.1365-4362.1986.tb02249.x. [DOI] [PubMed] [Google Scholar]
  16. Smit H. A., Coenraads P. J. Epidemiology of contact dermatitis. Monogr Allergy. 1993;31:29–48. [PubMed] [Google Scholar]
  17. Smith J. M. Incidence of atopic disease. Med Clin North Am. 1974 Jan;58(1):3–24. doi: 10.1016/s0025-7125(16)32173-3. [DOI] [PubMed] [Google Scholar]
  18. Strachan D. P., Golding J., Anderson H. R. Regional variations in wheezing illness in British children: effect of migration during early childhood. J Epidemiol Community Health. 1990 Sep;44(3):231–236. doi: 10.1136/jech.44.3.231. [DOI] [PMC free article] [PubMed] [Google Scholar]
  19. Strachan D. P. Hay fever, hygiene, and household size. BMJ. 1989 Nov 18;299(6710):1259–1260. doi: 10.1136/bmj.299.6710.1259. [DOI] [PMC free article] [PubMed] [Google Scholar]
  20. Taylor B., Wadsworth J., Wadsworth M., Peckham C. Changes in the reported prevalence of childhood eczema since the 1939-45 war. Lancet. 1984 Dec 1;2(8414):1255–1257. doi: 10.1016/s0140-6736(84)92805-8. [DOI] [PubMed] [Google Scholar]
  21. Waters W. E. Migraine: intelligence, social class, and familial prevalence. Br Med J. 1971 Apr 10;2(5753):77–81. doi: 10.1136/bmj.2.5753.77. [DOI] [PMC free article] [PubMed] [Google Scholar]

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