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. 1987 Mar;61(3):937–939. doi: 10.1128/jvi.61.3.937-939.1987

Role of the agnoprotein in regulation of simian virus 40 replication and maturation pathways.

M H Hou-Jong, S H Larsen, A Roman
PMCID: PMC254043  PMID: 3027418

Abstract

Analysis of two agnogene mutants, dl2304 deleted over the entire agnogene and in2379 carrying a 2-base insert, indicated that the mutant phenotype of small plaque formation must be the result of a defect late in the maturation pathway. Both mutants were removed from the pool of molecules available for replication with wild-type kinetics. Whereas dl2304 was somewhat reduced in its rate of progression from chromatin to previrions-virions, in2379, which produced even smaller plaques than dl2304 did, progressed with wild-type kinetics. Therefore, the agnoprotein was not required for progression from chromatin to previrions.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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