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. 1984 Jul;51(1):77–80. doi: 10.1128/jvi.51.1.77-80.1984

Laboratory and wild-derived mice with multiple loci for production of xenotropic murine leukemia virus.

C A Kozak, J W Hartley, H C Morse 3rd
PMCID: PMC254402  PMID: 6328046

Abstract

Mendelian segregation analysis was used to define genetic loci for the induction of infectious xenotropic murine leukemia virus in several laboratory and wild-derived mice. MA/My mice contain two loci for xenotropic virus inducibility, one of which, Bxv -1, is the only induction locus carried by five other inbred strains. The second, novel MA/My locus, designated Mxv -1, is unlinked to Bxv -1 and shows a lower efficiency of virus induction. The NZB mouse carries two induction loci; both are distinct from Bxv -1 since neither is linked to the Pep-3 locus on chromosome 1. Finally, one partially inbred strain derived from the wild Japanese mouse, Mus musculus molossinus, carries multiple (at least three) unlinked loci for induction of xenotropic virus. Although it is probable that inbred strains inherited xenotropic virus inducibility from Japanese mice, our data suggest that none of the induction loci carried by this particular M. m. molossinus strain are allelic with Bxv -1.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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