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. 1984 Jul;51(1):263–265. doi: 10.1128/jvi.51.1.263-265.1984

Localization of a type-specific antigenic site on herpes simplex virus type 2 glycoprotein D.

W E Rawls, N Balachandran, G Sisson, R J Watson
PMCID: PMC254429  PMID: 6202883

Abstract

A herpes simplex virus type 1 strain isolated from a recurrent lesion of the nose reacted with monoclonal antibodies recognizing a type 2-specific site on glycoprotein D but not with monoclonal antibodies recognizing other type 2-specific sites. DNA sequence analysis of the glycoprotein D gene of the isolate revealed a single nucleotide alteration which changed the codon for asparagine to one encoding histidine at amino acid 97 in the protein. Histidine is located at this position in glycoprotein of herpes simplex virus type 2; thus, the monoclonal antibody 17 beta A3 recognizes an epitope located at this region of the protein.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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