Abstract
Electron micrographs of negatively stained nucleocapsids isolated from intact, wild-type phi 6 bacteriophage revealed three distinct morphological forms. Two-dimensional analysis of electron micrographs of two of these forms and image averaging of all forms are consistent with a dodecahedral structure embodied in the phi 6 nucleocapsid.
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- Bamford D. H., Palva E. T., Lounatmaa K. Ultrastructure and life cycle of the lipid-containing bacteriophage phi 6. J Gen Virol. 1976 Aug;32(2):249–259. doi: 10.1099/0022-1317-32-2-249. [DOI] [PubMed] [Google Scholar]
- Bamford D. H., Palva E. T. Structure of the lipid-containing bacteriophage phi 6. Disruption by Triton X-100 treatment. Biochim Biophys Acta. 1980 Sep 18;601(2):245–259. doi: 10.1016/0005-2736(80)90530-1. [DOI] [PubMed] [Google Scholar]
- CASPAR D. L., KLUG A. Physical principles in the construction of regular viruses. Cold Spring Harb Symp Quant Biol. 1962;27:1–24. doi: 10.1101/sqb.1962.027.001.005. [DOI] [PubMed] [Google Scholar]
- Day L. A., Mindich L. The molecular weight of bacteriophage phi 6 and its nucleocapsid. Virology. 1980 Jun;103(2):376–385. doi: 10.1016/0042-6822(80)90196-8. [DOI] [PubMed] [Google Scholar]
- Emori Y., Iba H., Okada Y. Morphogenetic pathway of bacteriophage phi 6. A flow analysis of subviral and viral particles in infected cells. J Mol Biol. 1982 Jan 15;154(2):287–310. doi: 10.1016/0022-2836(82)90065-1. [DOI] [PubMed] [Google Scholar]
- Etten J. V., Lane L., Gonzalez C., Partridge J., Vidaver A. Comparative properties of bacteriophage phi6 and phi6 nucleocapsid. J Virol. 1976 May;18(2):652–658. doi: 10.1128/jvi.18.2.652-658.1976. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Gonzalez C. F., Langenberg W. G., Van Etten J. L., Vidaver A. K. Ultrastructure of bacteriophage phi 6: arrangement of the double-stranded RNA and envelope. J Gen Virol. 1977 May;35(2):353–359. doi: 10.1099/0022-1317-35-2-353. [DOI] [PubMed] [Google Scholar]
- Henderson C. E., Perham R. N., Finch J. T. Structure and symmetry of B. stearothermophilus pyruvate dehydrogenase multienzyme complex and implications for eucaryote evolution. Cell. 1979 May;17(1):85–93. doi: 10.1016/0092-8674(79)90297-6. [DOI] [PubMed] [Google Scholar]
- Herzberg K., Lang D., Reuss K., Dahn R. Uber das Verhalten der Filamente des Kanarienpockenvirus und der Capsomeren des Varizellen-Zostervirus gegenüber Lösemitteln und Fermenten. Zentralbl Bakteriol Orig. 1964 Dec;195(2):133–147. [PubMed] [Google Scholar]
- Jamison R. M. Morphology of echovirus 22. J Virol. 1969 Dec;4(6):904–906. doi: 10.1128/jvi.4.6.904-906.1969. [DOI] [PMC free article] [PubMed] [Google Scholar]
- KLUG A., CASPAR D. L. The structure of small viruses. Adv Virus Res. 1960;7:225–325. doi: 10.1016/s0065-3527(08)60012-3. [DOI] [PubMed] [Google Scholar]
- Klug A. Architectural design of spherical viruses. Nature. 1983 Jun 2;303(5916):378–379. doi: 10.1038/303378a0. [DOI] [PubMed] [Google Scholar]
- MUELLER G., PETERS D. SUBSTRUKTUREN DES VACCINEVIRUS, DARGESTELLT DURCH NEGATIVKONTRASTIERUNG. Arch Gesamte Virusforsch. 1963 Aug 26;13:435–451. [PubMed] [Google Scholar]
- Mindich L., Davidoff-Abelson R. The characterization of a 120 S particle formed during phi 6 infection. Virology. 1980 Jun;103(2):386–391. doi: 10.1016/0042-6822(80)90197-x. [DOI] [PubMed] [Google Scholar]
- Semancik J. S., Vidaver A. K., Van Etten J. L. Characterization of segmented double-helical RNA from bacteriophage phi6. J Mol Biol. 1973 Aug 25;78(4):617–625. doi: 10.1016/0022-2836(73)90283-0. [DOI] [PubMed] [Google Scholar]
- Vidaver A. K., Koski R. K., Van Etten J. L. Bacteriophage phi6: a Lipid-Containing Virus of Pseudomonas phaseolicola. J Virol. 1973 May;11(5):799–805. doi: 10.1128/jvi.11.5.799-805.1973. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Yamamoto K. R., Alberts B. M., Benzinger R., Lawhorne L., Treiber G. Rapid bacteriophage sedimentation in the presence of polyethylene glycol and its application to large-scale virus purification. Virology. 1970 Mar;40(3):734–744. doi: 10.1016/0042-6822(70)90218-7. [DOI] [PubMed] [Google Scholar]
- Yang Y., Lang D. Electron microscopy of bacteriophage phi 6 nucleocapsid: three-dimensional image analysis. J Virol. 1984 Aug;51(2):484–488. doi: 10.1128/jvi.51.2.484-488.1984. [DOI] [PMC free article] [PubMed] [Google Scholar]