Abstract
Details of consumption of hypnotic drugs derived from a nationally representative sample of elderly people were analysed in terms of the prevalence, duration, and likely frequency of use. Of 1020 randomly selected subjects aged 65 and over 16% (166) reported using (mainly benzodiazepine) hypnotic drugs, and of these 89% reported having taken such a drug the night before the interview. Most of these users (73%) had been taking hypnotic drugs for more than one year, with 25% reporting drug use for more than 10 years.
These results suggest that for most elderly users of hypnotic drugs, patterns of consumption encourage the development of cumulative effects and benzodiazepine dependence.
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- Adam K., Oswald I., Shapiro C. Effects of loprazolam and of triazolam on sleep and overnight urinary cortisol. Psychopharmacology (Berl) 1984;82(4):389–394. doi: 10.1007/BF00427692. [DOI] [PubMed] [Google Scholar]
- Ebrahim S., Morgan K., Dallosso H., Bassey J., Harries U., Terry A. Interviewing the elderly about their health: validity and effects on family doctor contacts. Age Ageing. 1987 Jan;16(1):52–57. doi: 10.1093/ageing/16.1.52. [DOI] [PubMed] [Google Scholar]
- Evans J. G., Jarvis E. H. Nitrazepam and the elderly. Br Med J. 1972 Nov 25;4(5838):487–487. doi: 10.1136/bmj.4.5838.487-a. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Greenblatt D. J., Allen M. D. Toxicity of nitrazepam in the elderly: a report from the Boston Collaborative Drug Surveillance Program. Br J Clin Pharmacol. 1978 May;5(5):407–413. doi: 10.1111/j.1365-2125.1978.tb01646.x. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Higgitt A. C., Lader M. H., Fonagy P. Clinical management of benzodiazepine dependence. Br Med J (Clin Res Ed) 1985 Sep 14;291(6497):688–690. doi: 10.1136/bmj.291.6497.688. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Morgan K., Dallosso H. M., Arie T., Byrne E. J., Jones R., Waite J. Mental health and psychological well-being among the old and the very old living at home. Br J Psychiatry. 1987 Jun;150:801–807. doi: 10.1192/bjp.150.6.801. [DOI] [PubMed] [Google Scholar]
- Morgan K. Effects of repeated dose nitrazepam and lormetazepam on psychomotor performance in the elderly. Psychopharmacology (Berl) 1985;86(1-2):209–211. doi: 10.1007/BF00431711. [DOI] [PubMed] [Google Scholar]
- Morgan K., Oswald I. Anxiety caused by a short-life hypnotic. Br Med J (Clin Res Ed) 1982 Mar 27;284(6320):942–942. doi: 10.1136/bmj.284.6320.942. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Morgan K. Sedative-hypnotic drug use and ageing. Arch Gerontol Geriatr. 1983 Nov;2(3):181–199. doi: 10.1016/0167-4943(83)90022-5. [DOI] [PubMed] [Google Scholar]