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. 1988 May 28;296(6635):1498–1500. doi: 10.1136/bmj.296.6635.1498

Low birth weight and risk of high blood pressure in adulthood

Gerhard Gennser, Per Rymark, Per Erik Isberg
PMCID: PMC2546017  PMID: 3134084

Abstract

Hospital birth records were sought for 104 men from a pool of male army conscripts with “normal” or “high” blood pressure when measured at 28 years of age. Of 77 men whose birth weight and date of the mother's last menstrual period before the pregnancy could be found, 25 had a resting diastolic blood pressure of ≥90 mm Hg. In 11 of these compared with nine of the 52 men with normal diastolic pressures their birth weights in relation to gestational age had been below the mean and 1 SD of a comparable Swedish population. The risk of increased diastolic blood pressure in early adult life was significantly higher among men who had been growth retarded at birth than among those whose birth weight had been appropriate for gestational age (odds ratio 3·63; 95% confidence interval 1·14 to 12·57).

Being born small for gestational age may be a predictor of raised blood pressure in early adult life.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. Biron P., Mongeau J. G. Familial aggregation of blood pressure and its components. Pediatr Clin North Am. 1978 Feb;25(1):29–33. doi: 10.1016/s0031-3955(16)33529-5. [DOI] [PubMed] [Google Scholar]
  2. CHESLEY L. C., COSGROVE R. A., ANNITTO J. E. A follow-up of eclamptic women. Fourth periodic report. Am J Obstet Gynecol. 1962 May 15;83:1360–1372. doi: 10.1016/s0002-9378(16)36049-5. [DOI] [PubMed] [Google Scholar]
  3. Chesley L. C., Cooper D. W. Genetics of hypertension in pregnancy: possible single gene control of pre-eclampsia and eclampsia in the descendants of eclamptic women. Br J Obstet Gynaecol. 1986 Sep;93(9):898–908. doi: 10.1111/j.1471-0528.1986.tb08006.x. [DOI] [PubMed] [Google Scholar]
  4. Giles W. B., Trudinger B. J., Baird P. J. Fetal umbilical artery flow velocity waveforms and placental resistance: pathological correlation. Br J Obstet Gynaecol. 1985 Jan;92(1):31–38. doi: 10.1111/j.1471-0528.1985.tb01045.x. [DOI] [PubMed] [Google Scholar]
  5. Griffin D., Cohen-Overbeek T., Campbell S. Fetal and utero-placental blood flow. Clin Obstet Gynaecol. 1983 Dec;10(3):565–602. [PubMed] [Google Scholar]
  6. Havlik R. J., Garrison R. J., Feinleib M., Kannel W. B., Castelli W. P., McNamara P. M. Blood pressure aggregation in families. Am J Epidemiol. 1979 Sep;110(3):304–312. doi: 10.1093/oxfordjournals.aje.a112815. [DOI] [PubMed] [Google Scholar]
  7. Keirse M. J. Epidemiology and aetiology of the growth retarded baby. Clin Obstet Gynaecol. 1984 Aug;11(2):415–436. [PubMed] [Google Scholar]
  8. Kotchen J. M., Kotchen T. A., Cottrill C. M., Guthrie G. P., Jr, Somes G. Blood pressures of young mothers and their first children 3-6 years following hypertension during pregnancy. J Chronic Dis. 1979;32(9-10):653–659. doi: 10.1016/0021-9681(79)90095-x. [DOI] [PubMed] [Google Scholar]
  9. Langford H. G., Watson R. L. Prepregnant blood pressure, hypertension during pregnancy, and later blood pressure of mothers and offspring. Hypertension. 1980 Jul-Aug;2(4 Pt 2):130–133. [PubMed] [Google Scholar]
  10. Lauer R. M., Anderson A. R., Beaglehole R., Burns T. L. Factors related to tracking of blood pressure in children. U.S. National Center for Health Statistics Health Examination Surveys Cycles II and III. Hypertension. 1984 May-Jun;6(3):307–314. doi: 10.1161/01.hyp.6.3.307. [DOI] [PubMed] [Google Scholar]
  11. Persson P. H., Weldner B. M. Intra-uterine weight curves obtained by ultrasound. Acta Obstet Gynecol Scand. 1986;65(2):169–173. doi: 10.3109/00016348609158374. [DOI] [PubMed] [Google Scholar]
  12. Theorell T., Knox S., Svensson J., Waller D. Blood pressure variations during a working day at age 28: effects of different types of work and blood pressure level at age 18. J Human Stress. 1985 Spring;11(1):36–41. doi: 10.1080/0097840X.1985.9936736. [DOI] [PubMed] [Google Scholar]
  13. Trudinger B. J., Giles W. B., Cook C. M., Bombardieri J., Collins L. Fetal umbilical artery flow velocity waveforms and placental resistance: clinical significance. Br J Obstet Gynaecol. 1985 Jan;92(1):23–30. doi: 10.1111/j.1471-0528.1985.tb01044.x. [DOI] [PubMed] [Google Scholar]
  14. Zinner S. H., Levy P. S., Kass E. H. Familial aggregation of blood pressure in childhood. N Engl J Med. 1971 Feb 25;284(8):401–404. doi: 10.1056/NEJM197102252840801. [DOI] [PubMed] [Google Scholar]

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