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. 1985 Mar;53(3):827–833. doi: 10.1128/jvi.53.3.827-833.1985

Isolation from cats of an endogenous type C virus with a novel envelope glycoprotein.

D K Haapala, W G Robey, S D Oroszlan, W P Tsai
PMCID: PMC254714  PMID: 2983093

Abstract

A search for variant endogenous cat viruses led to a novel isolate. Although the major envelope glycoprotein of this virus was similar in size to that of an RD-114-like virus that was coisolated, it was unrelated to RD-114 or feline leukemia virus by immunological and biological criteria. This degree of dissimilarity suggests a different evolutionary progenitor from that for the RD-114 and feline leukemia virus viral envelopes. The novel virus did, however, code for gag gene polypeptides which are closely related to RD-114 virus. Neither the novel isolate nor the RD-114-like coisolate induced foci in S+L- cat cells which restrict focus induction by RD-114 virus. This suggests that the two viruses share a common genomic target of restriction which resides outside of the env region.

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Selected References

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  1. Anderson L. J., Jarrett W. F., Jarrett O., Laird H. M. Feline leukemia-virus infection of kittens: mortality associated with atrophy of the thymus and lymphoid depletion. J Natl Cancer Inst. 1971 Oct;47(4):807–817. [PubMed] [Google Scholar]
  2. Barré-Sinoussi F., Chermann J. C., Rey F., Nugeyre M. T., Chamaret S., Gruest J., Dauguet C., Axler-Blin C., Vézinet-Brun F., Rouzioux C. Isolation of a T-lymphotropic retrovirus from a patient at risk for acquired immune deficiency syndrome (AIDS). Science. 1983 May 20;220(4599):868–871. doi: 10.1126/science.6189183. [DOI] [PubMed] [Google Scholar]
  3. Bassin R. H., Phillips L. A., Kramer M. J., Haapala D. K., Peebles P. T., Nomura S., Fischinger P. J. Properties of 3T3 cells transformed by murine sarcoma virus in the absence of replicating murine leukemia helper virus. Bibl Haematol. 1973;39:272–280. doi: 10.1159/000427853. [DOI] [PubMed] [Google Scholar]
  4. Bassin R. H., Ruscetti S., Ali I., Haapala D. K., Rein A. Normal DBA/2 mouse cells synthesize a glycoprotein which interferes with MCF virus infection. Virology. 1982 Nov;123(1):139–151. doi: 10.1016/0042-6822(82)90301-4. [DOI] [PubMed] [Google Scholar]
  5. Bassin R. H., Tuttle N., Fischinger P. J. Isolation of murine sarcoma virus-transformed mouse cells which are negative for leukemia virus from agar suspension cultures. Int J Cancer. 1970 Jul 15;6(1):95–107. doi: 10.1002/ijc.2910060114. [DOI] [PubMed] [Google Scholar]
  6. Crandell R. A., Fabricant C. G., Nelson-Rees W. A. Development, characterization, and viral susceptibility of a feline (Felis catus) renal cell line (CRFK). In Vitro. 1973 Nov-Dec;9(3):176–185. doi: 10.1007/BF02618435. [DOI] [PubMed] [Google Scholar]
  7. Declève A., Niwa O., Gelmann E., Kaplan H. S. Replication kinetics of N- and B-tropic murine leukemia viruses on permissive and nonpermissive cells in vitro. Virology. 1975 Jun;65(2):320–332. doi: 10.1016/0042-6822(75)90038-0. [DOI] [PubMed] [Google Scholar]
  8. DesGroseillers L., Jolicoeur P. Physical mapping of the Fv-1 tropism host range determinant of BALB/c murine leukemia viruses. J Virol. 1983 Dec;48(3):685–696. doi: 10.1128/jvi.48.3.685-696.1983. [DOI] [PMC free article] [PubMed] [Google Scholar]
  9. Duran-Troise G., Bassin R. H., Rein A., Gerwin B. I. Loss of Fv-1 restriction in Balb/3T3 cells following infection with a single N tropic murine leukemia virus particle. Cell. 1977 Mar;10(3):479–488. doi: 10.1016/0092-8674(77)90035-6. [DOI] [PubMed] [Google Scholar]
  10. Essex M., McLane M. F., Lee T. H., Falk L., Howe C. W., Mullins J. I., Cabradilla C., Francis D. P. Antibodies to cell membrane antigens associated with human T-cell leukemia virus in patients with AIDS. Science. 1983 May 20;220(4599):859–862. doi: 10.1126/science.6342136. [DOI] [PubMed] [Google Scholar]
  11. Fischinger P. J., Haapala D. K. Quantitative interactions of feline leukaemia virus and its pseudotype of murine sarcoma virus in cat cells: requirement for DNA synthesis. J Gen Virol. 1971 Nov;13(2):203–214. doi: 10.1099/0022-1317-13-2-203. [DOI] [PubMed] [Google Scholar]
  12. Fischinger P. J., Nomura S., Blevins C. S., Bolognesi D. P. Two levels of restriction by mouse or cat cells of murine sarcoma virus coated by endogenous xenotropic oncornavirus. J Gen Virol. 1975 Oct;29(1):51–62. doi: 10.1099/0022-1317-29-1-51. [DOI] [PubMed] [Google Scholar]
  13. Fischinger P. J., Peebles P. T., Nomura S., Haapala D. K. Isolation of RD-114-like oncornavirus from a cat cell line. J Virol. 1973 Jun;11(6):978–985. doi: 10.1128/jvi.11.6.978-985.1973. [DOI] [PMC free article] [PubMed] [Google Scholar]
  14. Fishinger P. J., Moore C. O. The formation and nature of foci induced by a modified sarcoma virus in human cells. J Gen Virol. 1971 Jul;12(1):59–63. doi: 10.1099/0022-1317-12-1-59. [DOI] [PubMed] [Google Scholar]
  15. Franklin R. B., Maldonado R. L., Bose H. R. Isolation and characterization of reticuloendotheliosis virus transformed bone marrow cells. Intervirology. 1974;3(5-6):342–352. doi: 10.1159/000149771. [DOI] [PubMed] [Google Scholar]
  16. Gallo R. C., Sarin P. S., Gelmann E. P., Robert-Guroff M., Richardson E., Kalyanaraman V. S., Mann D., Sidhu G. D., Stahl R. E., Zolla-Pazner S. Isolation of human T-cell leukemia virus in acquired immune deficiency syndrome (AIDS). Science. 1983 May 20;220(4599):865–867. doi: 10.1126/science.6601823. [DOI] [PubMed] [Google Scholar]
  17. Hardy W. D., Jr, Old L. J., Hess P. W., Essex M., Cotter S. Horizontal transmission of feline leukaemia virus. Nature. 1973 Aug 3;244(5414):266–269. doi: 10.1038/244266a0. [DOI] [PubMed] [Google Scholar]
  18. Hartley J. W., Rowe W. P., Huebner R. J. Host-range restrictions of murine leukemia viruses in mouse embryo cell cultures. J Virol. 1970 Feb;5(2):221–225. doi: 10.1128/jvi.5.2.221-225.1970. [DOI] [PMC free article] [PubMed] [Google Scholar]
  19. Hopkins N., Schindler J., Hynes R. Six-NB-tropic murine leukemia viruses derived from a B-tropic virus of BALB/c have altered p30. J Virol. 1977 Jan;21(1):309–318. doi: 10.1128/jvi.21.1.309-318.1977. [DOI] [PMC free article] [PubMed] [Google Scholar]
  20. Jarrett W., Jarrett O., Mackey L., Laird H., Hardy W., Jr, Essex M. Horizontal transmission of leukemia virus and leukemia in the cat. J Natl Cancer Inst. 1973 Sep;51(3):833–841. doi: 10.1093/jnci/51.3.833. [DOI] [PubMed] [Google Scholar]
  21. Jolicoeur P. The Fv-1 gene of the mouse and its control of murine leukemia virus replication. Curr Top Microbiol Immunol. 1979;86:67–122. doi: 10.1007/978-3-642-67341-2_3. [DOI] [PubMed] [Google Scholar]
  22. Laemmli U. K. Cleavage of structural proteins during the assembly of the head of bacteriophage T4. Nature. 1970 Aug 15;227(5259):680–685. doi: 10.1038/227680a0. [DOI] [PubMed] [Google Scholar]
  23. Levy J. A. Autoimmunity and neoplasia. The possible role of C-type viruses. Am J Clin Pathol. 1974 Aug;62(2):258–280. doi: 10.1093/ajcp/62.2.258. [DOI] [PubMed] [Google Scholar]
  24. Morgan M. A., Copeland T. D., Oroszlan S. Structural and antigenic analysis of the nucleic acid-binding proteins of bovine and feline leukemia viruses. J Virol. 1983 Apr;46(1):177–186. doi: 10.1128/jvi.46.1.177-186.1983. [DOI] [PMC free article] [PubMed] [Google Scholar]
  25. Noronha F., Dougherty E., Poco A., Gries C., Post J., Rickard C. Cytological and serological studies of a feline endogenous C-type virus. Arch Gesamte Virusforsch. 1974;45(3):235–248. doi: 10.1007/BF01249686. [DOI] [PubMed] [Google Scholar]
  26. O'CONNOR T. E., RAUSCHER F. J., ZEIGEL R. F. DENSITY GRADIENT CENTRIFUGATION OF A MURINE LEUKEMIA VIRUS. Science. 1964 May 29;144(3622):1144–1147. doi: 10.1126/science.144.3622.1144. [DOI] [PubMed] [Google Scholar]
  27. Oroszlan S., Bova D., Martin White M. H., Toni R., Foreman C., Gilden R. V. Purification and immunological characterization of the major internal protein of the RD-114 virus. Proc Natl Acad Sci U S A. 1972 May;69(5):1211–1215. doi: 10.1073/pnas.69.5.1211. [DOI] [PMC free article] [PubMed] [Google Scholar]
  28. Ou C. Y., Boone L. R., Koh C. K., Tennant R. W., Yang W. K. Nucleotide sequences of gag-pol regions that determine the Fv-1 host range property of BALB/c N-tropic and B-tropic murine leukemia viruses. J Virol. 1983 Dec;48(3):779–784. doi: 10.1128/jvi.48.3.779-784.1983. [DOI] [PMC free article] [PubMed] [Google Scholar]
  29. Pang R. H., Phillips L. A., Haapala D. K. Characterization of Gazdar murine sarcoma virus by nucleic acid hybridization and analysis of viral expression in cells. J Virol. 1977 Nov;24(2):551–556. doi: 10.1128/jvi.24.2.551-556.1977. [DOI] [PMC free article] [PubMed] [Google Scholar]
  30. Peebles P. T. An in vitro focus-induction assay for xenotropic murine leukemia virus, feline leukemia virus C, and the feline--primate viruses RD-114/CCC/M-7. Virology. 1975 Sep;67(1):288–291. doi: 10.1016/0042-6822(75)90427-4. [DOI] [PubMed] [Google Scholar]
  31. Pincus T., Hartley J. W., Rowe W. P. A major genetic locus affecting resistance to infection with murine leukemia viruses. IV. Dose-response relationships in Fv-1-sensitive and resistant cell cultures. Virology. 1975 Jun;65(2):333–342. doi: 10.1016/0042-6822(75)90039-2. [DOI] [PubMed] [Google Scholar]
  32. Rasheed S., Gardner M. B. Isolation of feline leukemia virus from a leopard cat cell line and search for retrovirus in wild felidae. J Natl Cancer Inst. 1981 Oct;67(4):929–933. [PubMed] [Google Scholar]
  33. Richert N. D., Davies P. J., Jay G., Pastan I. H. Characterization of an immune complex kinase in immunoprecipitates of avian sarcoma virus-transformed fibroblasts. J Virol. 1979 Sep;31(3):696–706. doi: 10.1128/jvi.31.3.696-706.1979. [DOI] [PMC free article] [PubMed] [Google Scholar]
  34. Robey W. G., Oskarsson M. K., Vande Woude G. F., Naso R. B., Arlinghaus R. B., Haapala D. K., Fischinger P. J. Cells transformed by certain strains of Moloney sarcoma virus contain murine p60. Cell. 1977 Jan;10(1):79–89. doi: 10.1016/0092-8674(77)90142-8. [DOI] [PubMed] [Google Scholar]
  35. Sarma P. S., Log T. Subgroup classification of feline leukemia and sarcoma viruses by viral interference and neutralization tests. Virology. 1973 Jul;54(1):160–169. doi: 10.1016/0042-6822(73)90125-6. [DOI] [PubMed] [Google Scholar]
  36. Shih T. Y., Weeks M. O., Young H. A., Scolnick E. M. p21 of Kirsten murine sarcoma virus is thermolabile in a viral mutant temperature sensitive for the maintenance of transformation. J Virol. 1979 Aug;31(2):546–546. doi: 10.1128/jvi.31.2.546-546.1979. [DOI] [PMC free article] [PubMed] [Google Scholar]
  37. Symington J., Green M., Brackmann K. Immunoautoradiographic detection of proteins after electrophoretic transfer from gels to diazo-paper: analysis of adenovirus encoded proteins. Proc Natl Acad Sci U S A. 1981 Jan;78(1):177–181. doi: 10.1073/pnas.78.1.177. [DOI] [PMC free article] [PubMed] [Google Scholar]

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