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The Journal of Automatic Chemistry logoLink to The Journal of Automatic Chemistry
. 1991;13(3):93–95. doi: 10.1155/S1463924691000172

The hydrolysis of proteins by microwave energy

Sam A Margolis 1, Lois Jassie 1, H M Kingston 1
PMCID: PMC2547911  PMID: 18924889

Abstract

Microwave energy, at manually-adjusted, partial power settings has been used to hydrolyse bovine serum albumin at 125 °C. Hydrolysis was complete within 2 h, except for valine and isoleucine which were completely liberated within 4 h. The aminoacid destruction was less than that observed at similar hydrolysis conditions with other methods and complete hydrolysis was achieved more rapidly. These results provide a basis for automating the process of amino-acid hydrolysis.

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