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. 1985 May;54(2):304–310. doi: 10.1128/jvi.54.2.304-310.1985

Induction of angiosarcoma by a c-erbB transducing virus.

S E Tracy, B A Woda, H L Robinson
PMCID: PMC254798  PMID: 2985799

Abstract

Recently, 12 new transductions of c-erbB have been identified in a series of Rous-associated virus type 1-induced erythroleukemias. During the passage of these new transducing viruses it has become apparent that the erythroleukemia in chicken 5005 contained two different c-erbB transducing viruses. One induces erythroblastosis, whereas the second induces angiosarcoma. The angiosarcoma- and erythroblastosis-inducing viruses appear to have had a common ancestor, since tumors induced by each contain a novel, 4.3-kilobase c-erbB-related EcoRI fragment. The angiosarcoma-inducing virus has been named avian angiosarcoma virus and is designated for the chicken in which it originated.

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Selected References

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