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. 1985 Aug;55(2):483–488. doi: 10.1128/jvi.55.2.483-488.1985

Potent neutralizing activity associated with anti-glycoprotein D specificity among monoclonal antibodies selected for binding to herpes simplex virions.

M F Para, M L Parish, A G Noble, P G Spear
PMCID: PMC254957  PMID: 2991571

Abstract

Thirty-three monoclonal antibodies were selected for ability to bind to purified virions of herpes simplex virus and were shown by immunoprecipitation to react with one or another of the envelope glycoproteins. Only six of these antibodies exhibited potent neutralizing activity, and all six were specific for glycoprotein D. Two other anti-glycoprotein D antibodies and 25 antibodies specific for four other viral glycoproteins had much less potent, if any, neutralizing activity.

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Selected References

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