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. 1985 Jan;53(1):299–301. doi: 10.1128/jvi.53.1.299-301.1985

Epstein-Barr virus transformation of human B lymphocytes despite inhibition of viral polymerase.

J W Sixbey, J S Pagano
PMCID: PMC255037  PMID: 2981351

Abstract

Epstein-Barr virus transformed human lymphocytes despite the presence of up to 500 microM acyclovir [9-(2-hydroxyethoxymethyl)guanine], a viral DNA polymerase inhibitor. The transformed cells contained multiple Epstein-Barr virus genome copy numbers. Functional viral DNA polymerase is probably not required for cell transformation and the initial amplification of the viral genome.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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