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Journal of Virology logoLink to Journal of Virology
. 1983 Apr;46(1):125–130. doi: 10.1128/jvi.46.1.125-130.1983

Sequence Determination of the (+) Leader RNA Regions of the Vesicular Stomatitis Virus Chandipura, Cocal, and Piry Serotype Genomes

Colomba Giorgi 1,, Benjamin Blumberg 1, Daniel Kolakofsky 1
PMCID: PMC255099  PMID: 6298450

Abstract

Using 3′-end-labeled genome probes, cells infected with vesicular stomatitis virus Chandipura, Cocal, and Piry serotypes were shown to contain (+) leader RNAs of approximately 50 nucleotides in length. The nucleotide sequence of the leader RNA regions of these genomes was determined and compared with the previously reported sequences of both the (+) and (-) leader RNA regions of other vesicular stomatitis virus serotypes. Regions of strong conservation of nucleotide sequence among the various vesicular stomatitis virus serotypes suggest those nucleotides thought to be involved in control functions during vesicular stomatitis virus replication.

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Selected References

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