Abstract
The minor glycoproteins from hepatitis B surface antigen, GP33 and GP36, contain at their carboxy-terminal part the sequence of the major protein P24. They have 55 additional amino acids at the amino-terminal part which are coded by the pre-S region of the viral DNA.
Full text
PDF![626](https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2e73/255166/9eb4bb254ee6/jvirol00146-0302.png)
![627](https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2e73/255166/94cb09ead421/jvirol00146-0303.png)
![628](https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2e73/255166/660d205c2c6a/jvirol00146-0304.png)
Images in this article
Selected References
These references are in PubMed. This may not be the complete list of references from this article.
- Galibert F., Chen T. N., Mandart E. Nucleotide sequence of a cloned woodchuck hepatitis virus genome: comparison with the hepatitis B virus sequence. J Virol. 1982 Jan;41(1):51–65. doi: 10.1128/jvi.41.1.51-65.1982. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Galibert F., Mandart E., Fitoussi F., Tiollais P., Charnay P. Nucleotide sequence of the hepatitis B virus genome (subtype ayw) cloned in E. coli. Nature. 1979 Oct 25;281(5733):646–650. doi: 10.1038/281646a0. [DOI] [PubMed] [Google Scholar]
- Gerlich W. H., Feitelson M. A., Marion P. L., Robinson W. S. Structural relationships between the surface antigens of ground squirrel hepatitis virus and human hepatitis B virus. J Virol. 1980 Dec;36(3):787–795. doi: 10.1128/jvi.36.3.787-795.1980. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Gerlich W., Thomssen R. Standardized detection of hepatitis B surface antigen: determination of its serum concentration in weight units per volume. Dev Biol Stand. 1975;30:78–87. [PubMed] [Google Scholar]
- Kozak M. Possible role of flanking nucleotides in recognition of the AUG initiator codon by eukaryotic ribosomes. Nucleic Acids Res. 1981 Oct 24;9(20):5233–5252. doi: 10.1093/nar/9.20.5233. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Laemmli U. K. Cleavage of structural proteins during the assembly of the head of bacteriophage T4. Nature. 1970 Aug 15;227(5259):680–685. doi: 10.1038/227680a0. [DOI] [PubMed] [Google Scholar]
- Machida A., Kishimoto S., Ohnuma H., Miyamoto H., Baba K., Oda K., Nakamura T., Funatsu G., Miyakawa Y., Mayumi M. A glycopeptide containing 15 amino acid residues derived from hepatitis B surface antigen particles: demonstration of immunogenicity to raise anti-HBs in mice. Mol Immunol. 1982 Sep;19(9):1087–1093. doi: 10.1016/0161-5890(82)90319-4. [DOI] [PubMed] [Google Scholar]
- Pasek M., Goto T., Gilbert W., Zink B., Schaller H., MacKay P., Leadbetter G., Murray K. Hepatitis B virus genes and their expression in E. coli. Nature. 1979 Dec 6;282(5739):575–579. doi: 10.1038/282575a0. [DOI] [PubMed] [Google Scholar]
- Peterson D. L. Isolation and characterization of the major protein and glycoprotein of hepatitis B surface antigen. J Biol Chem. 1981 Jul 10;256(13):6975–6983. [PubMed] [Google Scholar]
- Pourcel C., Louise A., Gervais M., Chenciner N., Dubois M. F., Tiollais P. Transcription of the hepatitis B surface antigen gene in mouse cells transformed with cloned viral DNA. J Virol. 1982 Apr;42(1):100–105. doi: 10.1128/jvi.42.1.100-105.1982. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Sanchez Y., Ionescu-Matiu I., Dreesman G. R., Hollinger F. B., Melnick J. L. Evidence for the presence of repeating antigenic determinants in the major polypeptides derived from hepatitis B surface antigen. Virology. 1981 Oct 15;114(1):71–80. doi: 10.1016/0042-6822(81)90253-1. [DOI] [PubMed] [Google Scholar]
- Skelly J., Howard C. R., Zuckerman A. J. The labelling of galactose residues in hepatitis B surface antigen glycoprotein. J Gen Virol. 1978 Dec;41(3):447–457. doi: 10.1099/0022-1317-41-3-447. [DOI] [PubMed] [Google Scholar]
- Stibbe W., Gerlich W. H. Variable protein composition of hepatitis B surface antigen from different donors. Virology. 1982 Dec;123(2):436–442. doi: 10.1016/0042-6822(82)90275-6. [DOI] [PubMed] [Google Scholar]