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. 1987 Jan;61(1):200–205. doi: 10.1128/jvi.61.1.200-205.1987

Genome RNA terminus conservation and diversity among vesiculoviruses.

S T Nichol, J J Holland
PMCID: PMC255238  PMID: 3023698

Abstract

Sequence analysis of the RNA genome termini of various vesiculovirus standard and defective interfering (DI) particles demonstrated that some virus regulatory sequences and domains of virus N protein are highly conserved while others show considerable divergence. Clearly, distinct RNA signal sequences and protein-coding regions of these virus genomes have quite different evolutionary pressures or constraints. Terminal regions of DI-particle RNA genomes of these viruses were found to possess self-complementary stems at the RNA termini, demonstrating the conservation of this DI-particle structural feature throughout the vesiculovirus group. A high degree of conservation of the 3'-terminal sequences of recent and historic isolates of vesicular stomatitis virus New Jersey was also demonstrated.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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