Abstract
Epidural metastasis is potentially one of the most disabling complications encountered in oncology. Once paraplegia has been established, only one patient in ten responds to treatment. A series of 16 patients is presented in which early diagnosis and treatment led to improvement in 13 of 16 patients. Most patients present with pain for varying periods (mean 2.2 months) before neurological signs appear. Myelography alone establishes the diagnosis. Spinal radiography correlates well with the block level in two thirds of cases. Radiotherapy, alone or with steroids, increasingly is used in the management of this condition.
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Selected References
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- BARRON K. D., HIRANO A., ARAKI S., TERRY R. D. Experiences with metastatic neoplasms involving the spinal cord. Neurology. 1959 Feb;9(2):91–106. doi: 10.1212/wnl.9.2.91. [DOI] [PubMed] [Google Scholar]
- Bruckman J. E., Bloomer W. D. Management of spinal cord compression. Semin Oncol. 1978 Jun;5(2):135–140. [PubMed] [Google Scholar]
- Friedman M., Kim T. H., Panahon A. M. Spinal cord compression in malignant lymphoma. Treatment and results. Cancer. 1976 Mar;37(3):1485–1491. doi: 10.1002/1097-0142(197603)37:3<1485::aid-cncr2820370334>3.0.co;2-l. [DOI] [PubMed] [Google Scholar]
- Gilbert H., Apuzzo M., Marshall L., Kagan A. R., Crue B., Wagner J., Fuchs K., Rush J., Rao A., Nussbaum H. Neoplastic epidural spinal cord compression. A current perspective. JAMA. 1978 Dec 15;240(25):2771–2773. [PubMed] [Google Scholar]
- Gilbert R. W., Kim J. H., Posner J. B. Epidural spinal cord compression from metastatic tumor: diagnosis and treatment. Ann Neurol. 1978 Jan;3(1):40–51. doi: 10.1002/ana.410030107. [DOI] [PubMed] [Google Scholar]
- Khan F. R., Glicksman A. S., Chu F. C., Nickson J. J. Treatment by radiotherapy of spinal cord compression due to extradural metastases. Radiology. 1967 Sep;89(3):495–500. doi: 10.1148/89.3.495. [DOI] [PubMed] [Google Scholar]
- Marshall L. F., Langfitt T. W. Combined therapy for metastatic extradural tumors of the spine. Cancer. 1977 Nov;40(5):2067–2070. doi: 10.1002/1097-0142(197711)40:5<2067::aid-cncr2820400512>3.0.co;2-h. [DOI] [PubMed] [Google Scholar]
- Raichle M. E., Posner J. B. The treatment of extradural spinal cord compression. Neurology. 1970 Apr;20(4):391–391. [PubMed] [Google Scholar]
- SMITH R. AN EVALUATION OF SURGICAL TREATMENT FOR SPINAL CORD COMPRESSION DUE TO METASTATIC CARCINOMA. J Neurol Neurosurg Psychiatry. 1965 Apr;28:152–158. doi: 10.1136/jnnp.28.2.152. [DOI] [PMC free article] [PubMed] [Google Scholar]