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letter
. 1981 Dec;73(12):1119–1121.

Disappearance of Soft Tissue 99mTc Diphosphonate Activity Following Radiation Therapy

Lawrence T Hill
PMCID: PMC2552782  PMID: 7328686

Abstract

The appearance of soft tissue concentrations of technitium labeled phosphate compounds has been observed in a variety of pathological conditions. The mechanism and pathophysiology of this phenomenon remain unclear.

Seven new patients diagnosed with lung cancer received 99mTc diphosphonate bone scans during the period of January 1975 to November 1975. Three of the seven subjects showed a significant accumulation of isotope in the region of the chest infiltrate at the time of diagnosis. Upon repeat technitium bone scans six months post radiation, two patients showed a sharp reduction in the soft tissue activity previously observed.

The material is presented and a possible explanation of this phenomenon is offered.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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