Skip to main content
Journal of Virology logoLink to Journal of Virology
. 1983 Sep;47(3):652–655. doi: 10.1128/jvi.47.3.652-655.1983

Antiviral activity released from Aedes albopictus cells persistently infected with Semliki forest virus.

S E Newton, L Dalgarno
PMCID: PMC255308  PMID: 6312089

Abstract

Aedes albopictus (mosquito) cells persistently infected with Semliki Forest virus released an agent which inhibited virus production by A. albopictus cells infected with homologous virus. Inhibition of virus production was accompanied by a marked reduction in the synthesis of viral RNA and viral proteins. Expression of the antiviral effect was prevented by pretreatment of cells with actinomycin. No analogous antiviral activity was detected in culture fluids of A. albopictus cells persistently infected with a flavivirus (Kunjin virus) or a bunyavirus (Bunyamwera virus).

Full text

PDF
652

Images in this article

Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. Davey M. W., Dalgarno L. Semliki Forest virus replication in cultured Aedes albopictus cells: studies on the establishment of persistence. J Gen Virol. 1974 Sep;24(3):453–463. doi: 10.1099/0022-1317-24-3-453. [DOI] [PubMed] [Google Scholar]
  2. Eaton B. T. Heterologous interference in Aedes albopictus cells infected with alphaviruses. J Virol. 1979 Apr;30(1):45–55. doi: 10.1128/jvi.30.1.45-55.1979. [DOI] [PMC free article] [PubMed] [Google Scholar]
  3. Igarashi A., Koo R., Stollar V. Evolution and properties of Aedes albopictus cell cultures persistently infected with sindbis virus. Virology. 1977 Oct 1;82(1):69–83. doi: 10.1016/0042-6822(77)90033-2. [DOI] [PubMed] [Google Scholar]
  4. Newton S. E., Short N. J., Dalgarno L. Bunyamwera virus replication in cultured Aedes albopictus (mosquito) cells: establishment of a persistent viral infection. J Virol. 1981 Jun;38(3):1015–1024. doi: 10.1128/jvi.38.3.1015-1024.1981. [DOI] [PMC free article] [PubMed] [Google Scholar]
  5. Newton S. E., Short N. J., Irving A. M., Dalgarno L. The Mapputta group of arboviruses: ultrastructural and molecular studies which place the group in the bunyavirus genus of the family Bunyaviridae. Aust J Exp Biol Med Sci. 1983 Apr;61(Pt 2):201–217. doi: 10.1038/icb.1983.19. [DOI] [PubMed] [Google Scholar]
  6. Richardson M. A., Boulton R. W., Raghow R. S., Dalgarno L. Polypeptide synthesis in alphavirus-infected Aedes albopictus cells during the establishment of persistent infection. Arch Virol. 1980;63(3-4):263–274. doi: 10.1007/BF01315032. [DOI] [PubMed] [Google Scholar]
  7. Riedel B., Brown D. T. Novel antiviral activity found in the media of Sindbis virus-persistently infected mosquito (Aedes albopictus) cell cultures. J Virol. 1979 Jan;29(1):51–60. doi: 10.1128/jvi.29.1.51-60.1979. [DOI] [PMC free article] [PubMed] [Google Scholar]
  8. Stollar V., Shenk T. E. Homologous viral interference in Aedes albopictus cultures chronically infected with Sindbis virus. J Virol. 1973 Apr;11(4):592–595. doi: 10.1128/jvi.11.4.592-595.1973. [DOI] [PMC free article] [PubMed] [Google Scholar]
  9. Tooker P., Kennedy S. I. Semliki Forest virus multiplication in clones of Aedes albopictus cells. J Virol. 1981 Feb;37(2):589–600. doi: 10.1128/jvi.37.2.589-600.1981. [DOI] [PMC free article] [PubMed] [Google Scholar]

Articles from Journal of Virology are provided here courtesy of American Society for Microbiology (ASM)

RESOURCES