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. 1984 Feb;49(2):315–318. doi: 10.1128/jvi.49.2.315-318.1984

Virally coded noncapsid protein associated with bovine parvovirus infection.

M Lederman, J T Patton, E R Stout, R C Bates
PMCID: PMC255467  PMID: 6319731

Abstract

A phosphorylated protein (NP-1) with an Mr of 28,000 has been detected in nuclei of bovine parvovirus (BPV)-infected cells in association with chromatin. No protein in this size range was detected after infection of appropriate cells with several autonomous rodent parvoviruses although the BPV-specific protein is similar in size to noncapsid proteins associated with rabbit parvovirus or adeno-associated virus infection. Structural homology between NP-1 and a BPV capsid protein could be detected by electrophoretic analysis of the products of proteolysis with chymotrypsin. This protein can be detected after in vitro translation of RNA from BPV-infected cells and BPV-specific RNA. Homology between the in vivo- and in vitro-synthesized species was shown by the similarity of the chymotryptic products.

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Selected References

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