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. 1964;30(6):845–853.

Segregation of genetic factors during recombination in Vibrio cholerae, strain 162

K Bhaskaran
PMCID: PMC2555083  PMID: 14215190

Abstract

In this paper an analysis of genetic recombinants derived from crosses between two mutant stocks of Vibrio cholerae, strain 162, differing from one another in nutritional requirements and other characters, is presented. It is shown that parent strains possessing a fertility factor (designated as the P factor) function as gene-donors while P- strains (without the P factor) serve as gene-recipients. Linkage between two genetic factors (purine and valine + isoleucine) is demonstrated and the probable sequence of seven genetic factors in the chromosome of V. cholerae, strain 162, is inferred.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. ALFOLDI L., JACOB F., WOLLMAN E. L., MAZE R. Sur le déterminisme génétique de la colicinogénie. C R Hebd Seances Acad Sci. 1958 Jun 23;246(25):3531–3533. [PubMed] [Google Scholar]
  2. BHASKARAN K., GORRILL R. H. A study of antigenic variation in Vibrio cholerae. J Gen Microbiol. 1957 Jun;16(3):721–729. doi: 10.1099/00221287-16-3-721. [DOI] [PubMed] [Google Scholar]
  3. BHASKARAN K. Genetic recombination in Vibrio cholerae. J Gen Microbiol. 1958 Aug;19(1):71–75. doi: 10.1099/00221287-19-1-71. [DOI] [PubMed] [Google Scholar]
  4. BHASKARAN K. Observations of the nature of genetic recombination in Vibrio cholerae. Indian J Med Res. 1959 May;47(3):253–260. [PubMed] [Google Scholar]
  5. BHASKARAN K., ROWLEY D. Nutritional studies on Vibrio cholerae. J Gen Microbiol. 1956 Oct;15(2):417–422. doi: 10.1099/00221287-15-2-417. [DOI] [PubMed] [Google Scholar]
  6. BHASKARAN K. Recombination of characters between mutant stocks of Vibrio cholerae, strain 162. J Gen Microbiol. 1960 Aug;23:47–54. doi: 10.1099/00221287-23-1-47. [DOI] [PubMed] [Google Scholar]
  7. CLOWES R. C. Colicine factors as fertility factors in bacteria: Escherichia coli K-12. Nature. 1961 Jun 10;190:988–989. doi: 10.1038/190988a0. [DOI] [PubMed] [Google Scholar]
  8. FARKAS-HIMSLEY H., SEYFRIED P. L. Lethal biosynthesis of a new antibacterial principle: vibriocin. Nature. 1962 Mar 24;193:1193–1194. doi: 10.1038/1931193a0. [DOI] [PubMed] [Google Scholar]
  9. HAYES W. Conjugation in Escherichia coli. Br Med Bull. 1962 Jan;18:36–40. doi: 10.1093/oxfordjournals.bmb.a069932. [DOI] [PubMed] [Google Scholar]
  10. HAYES W. Recombination in Bact. coli K 12; unidirectional transfer of genetic material. Nature. 1952 Jan 19;169(4290):118–119. doi: 10.1038/169118b0. [DOI] [PubMed] [Google Scholar]
  11. JACOB F., WOLLMAN E. L. Les épisomes, éléments génétiques ajoutés. C R Hebd Seances Acad Sci. 1958 Jul 7;247(1):154–156. [PubMed] [Google Scholar]
  12. Lederberg J. Gene Recombination and Linked Segregations in Escherichia Coli. Genetics. 1947 Sep;32(5):505–525. doi: 10.1093/genetics/32.5.505. [DOI] [PMC free article] [PubMed] [Google Scholar]
  13. SMITH S. M., STOCKER B. A. Colicinogeny and recombination. Br Med Bull. 1962 Jan;18:46–51. doi: 10.1093/oxfordjournals.bmb.a069934. [DOI] [PubMed] [Google Scholar]
  14. SNEATH P. H. Sex factors as episomes. Br Med Bull. 1962 Jan;18:41–45. doi: 10.1093/oxfordjournals.bmb.a069933. [DOI] [PubMed] [Google Scholar]
  15. ZINDER N. D., LEDERBERG J. Genetic exchange in Salmonella. J Bacteriol. 1952 Nov;64(5):679–699. doi: 10.1128/jb.64.5.679-699.1952. [DOI] [PMC free article] [PubMed] [Google Scholar]

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