Abstract
Complement-fixation and haemagglutination tests, utilizing a highly purified, specific Fraction 1 antigen of Pasteurella pestis, have been employed to detect specific plague antibody in the sera of rodents resident in a sylvatic plague focus. The data show that while the isolation of P. pestis is seasonal and rather rare, antibodies can be detected for long periods of time and with great frequency in rodents surviving infection. The authors recommend that serological methods be incorporated into epidemiological surveys and control programmes involving rodent plague.
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- BAKER E. E., SOMMER H., FOSTER L. E., MEYER E., MEYER K. F. Studies on immunization against plague. I. The isolation and characterization of the soluble antigen of Pasteurella pestis. J Immunol. 1952 Feb;68(2):131–145. [PubMed] [Google Scholar]
- BALTAZARD M., DAVIS D. H., DEVIGNAT R., GIRARD G., GOHAR M. A., KARTMAN L., MEYER K. F., PARKER M. T., POLLITZER R., PRINCE F. M. Recommended laboratory methods for the diagnosis of plague. Bull World Health Organ. 1956;14(3):457–509. [PMC free article] [PubMed] [Google Scholar]
- BHAGAVAN N. V., CHEN T. H., MEYER K. F. Further studies of antigenic structure of Pasteurella pestis in gels. Proc Soc Exp Biol Med. 1956 Mar;91(3):353–356. doi: 10.3181/00379727-91-22260. [DOI] [PubMed] [Google Scholar]
- CHEN T. H., MEYER K. F. Studies on immunization against plague. VII. A hemagglutination test with the protein fraction of Pasteurella pestis: a serologic comparison of virulent and avirulent strains with observations on the structure of the bacterial cells and its relationship to infection and immunity. J Immunol. 1954 Apr;72(4):282–298. [PubMed] [Google Scholar]
- CHEN T. H., MEYER K. F. Studies on immunization against plague. X. Specific precipitation of Pasteurella pestis antigens and antibodies in gels. J Immunol. 1955 Jun;74(6):501–507. [PubMed] [Google Scholar]
- CHEN T. H., QUAN S. F., MEYER K. F. Studies on immunization against plague. II. The complement-fixation test. J Immunol. 1952 Feb;68(2):147–158. [PubMed] [Google Scholar]
- KENT J. F., FIFE E. H., Jr Precise standardization of reagents for complement fixation. Am J Trop Med Hyg. 1963 Jan;12:103–116. doi: 10.4269/ajtmh.1963.12.103. [DOI] [PubMed] [Google Scholar]
- LAWTON W. D., FUKUI G. M., SURGALLA M. J. Studies on the antigens of Pasteurella pestis and Pasteurella pseudotuberculosis. J Immunol. 1960 May;84:475–479. [PubMed] [Google Scholar]
- MARCHETTE N. J., BUSHMAN J. B., PARKER D. D., JOHNSON E. E. Studies on infectious diseases in wild animals in Utah. IV. A wild rodent (Peromyscus spp.) plague focus in Utah. Zoonoses Res. 1962 Dec 31;1:341–361. [PubMed] [Google Scholar]
- SEVER J. L. Application of a microtechnique to viral serological investigations. J Immunol. 1962 Mar;88:320–329. [PubMed] [Google Scholar]
- THORPE B. D., MARCHETTE N. J., BUSHMAN J. B. Virulence studies of Pasteurella pestis isolates from the Great Salt Lake Desert. Am J Trop Med Hyg. 1963 Mar;12:219–222. doi: 10.4269/ajtmh.1963.12.219. [DOI] [PubMed] [Google Scholar]
- THORPE B. D., MARCHETTE N. J., BUSHMAN J. B. Virulence studies of Pasteurella pestis isolates from the Great Salt Lake Desert. Am J Trop Med Hyg. 1963 Mar;12:219–222. doi: 10.4269/ajtmh.1963.12.219. [DOI] [PubMed] [Google Scholar]