Abstract
An investigation carried out under WHO auspices in a small area of South India in 1950-55, and which covered a population of approximately 60 000, has not only shed light on various aspects of tuberculosis epidemiology, but has also served as an exercise in the practical conduct of a control campaign in a less developed area.
The programme was based essentially on systematic case-finding by mass miniature X-ray and tuberculin testing and the hospitalization of infectious cases. Its most dramatic effect on the community consisted in the great reduction of mortality—from 200 to 21 per 100 000 in less than four years—due no doubt to the advent of the newer antituberculosis drugs. This and other findings are discussed at length in the present report, which covers such topics as tuberculin sensitivity, infection rate, prevalence, incidence, and the results of a BCG control trial.
One of the conclusions reached as a result of the campaign was that domiciliary drug therapy had much to recommend it in an area such as this, given the reluctance of patients to enter hospital and thus be deprived of their earning capacity.
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- COCHRANE A. L., COX J. G., JARMAN T. F. A follow-up chest x-ray survey in the Rhondda Fach. I. Pulmonary tuberculosis. Br Med J. 1955 Feb 12;1(4910):371–378. doi: 10.1136/bmj.1.4910.371. [DOI] [PMC free article] [PubMed] [Google Scholar]
- D'ARCY HART P., POLLOCK T. M., SUTHERLAND I. Assessment of the first results of the Medical Research Council's trial of tuberculosis vaccines in adolescents in Great Britain. Bibl Tuberc. 1957;13(12):171–189. [PubMed] [Google Scholar]
- EDWARDS L. B., DRAGSTED I. BCG-vaccine studies. IV. Further observations on the effect of light on BCG vaccine. Bull World Health Organ. 1952;5(3):333–336. [PMC free article] [PubMed] [Google Scholar]
- EDWARDS L. B., TOLDERLUND K. BCG vaccine studies. III. Preliminary report on effect of sunlight and BCG vaccine. Bull World Health Organ. 1952;5(2):245–248. [PMC free article] [PubMed] [Google Scholar]
- GROTH-PETERSEN E., KNUDSEN J., WILBEK E. Konsekvensen af den aendrede epidemiologiske situation i tuberkulosearbejdet; tuberkulosemorbiditeten i den danske befolkning og i specifikke grupper af denne. Nord Med. 1957 Sep 19;58(38):1361–1369. [PubMed] [Google Scholar]
- GULD J. Quantitative aspects of the intradermal tuberculin test in humans. I. The dose-response function within the range 1-10 tuberculin units, determined by duplicate tests. Acta Tuberc Scand. 1953;28(3-4):222–245. [PubMed] [Google Scholar]
- MEYER S. N., HOUGEN A., EDWARDS P. Experimental error in the determination of tuberculin sensitivity. Public Health Rep. 1951 May 4;66(18):561–569. [PubMed] [Google Scholar]
- PALMER C. E., SHAW L. W., COMSTOCK G. W. Community trials of BCG vaccination. Am Rev Tuberc. 1958 Jun;77(6):877–907. doi: 10.1164/artpd.1958.77.6.877. [DOI] [PubMed] [Google Scholar]