Abstract
The appearance of resistance to both dieldrin and DDT in several malaria vectors has intensified investigations on the potential of organophosphorus compounds for residual application. This report describes the final year's activities of a three-year study on malathion. Water-wettable formulations of malathion and of Bayer 29493 were evaluated against DDT/dieldrin-resistant Anopheles albimanus in El Salvador.
The results indicate that neither compound at a dosage of 0.5 g/m2 offers any promise as a residual agent. At dosages of 1.0 g/m2 or 2.0 g/m2 the two toxicants gave effective kills (70%-100%) for periods of 21/2-3 months, based on 1-hour exposure to the treated surfaces. Up to 3 months, both compounds gave similar levels of effectiveness on wood, thatch, and mud. On whitewash and plaster surfaces, Bayer 29493 was superior to malathion.
The findings indicate that each insecticide has considerable potential value for residual treatment in areas where the malaria vector cannot be killed effectively by either DDT or dieldrin. In such areas, further investigation into their utility as replacements for the chlorinated hydrocarbon insecticides is warranted.
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