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. Author manuscript; available in PMC: 2009 Sep 1.
Published in final edited form as: Biochimie. 2008 May 23;90(9):1422–1426. doi: 10.1016/j.biochi.2008.05.010

FIGURE 2.

FIGURE 2

FIGURE 2

A- Selection for lentiviral genomic integration with blasticidin indicates a correlation between Metnase expression and the number of blasticidin-resistant colonies. B- Mutation of an essential residue in the transposase domain leads to decreased viral integration compared to wild-type Metnase U6- vector control, siMET- Metnase under-expressors, pCD- vector control, MET- Metnase over-expressors, D438A- over-expression of Metnase mutated in the transpose domain. *- statistically significant at p<0.05. All cell lines have the same colony forming potential without blasticidin selection.