Abstract
Ischaemic heart disease is almost invariably the result of atherosclerotic degeneration of the coronary arteries. However, other causes of ischaemic heart disease should always be considered. Here we describe two patients with a classic presentation of ischaemic heart disease resulting from acute leukaemia. The pathophysiological mechanisms of acute leukaemia leading to ischaemic heart disease are discussed.
Keywords: myocardial ischaemia, acute myeloid leukaemia, left ventricular function
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- Da Costa A., Isaaz K., Faure E., Mourot S., Cerisier A., Lamaud M. Clinical characteristics, aetiological factors and long-term prognosis of myocardial infarction with an absolutely normal coronary angiogram; a 3-year follow-up study of 91 patients. Eur Heart J. 2001 Aug;22(16):1459–1465. doi: 10.1053/euhj.2000.2553. [DOI] [PubMed] [Google Scholar]
- Jachmann-Jahn U., Cornely O. A., Laufs U., Höpp H. W., Meuthen I., Krakau M., O'Brien B. Acute anterior myocardial infarction as first manifestation of acute myeloid leukemia. Ann Hematol. 2001 Nov;80(11):677–681. doi: 10.1007/s002770100353. [DOI] [PubMed] [Google Scholar]
- Libby P. Molecular bases of the acute coronary syndromes. Circulation. 1995 Jun 1;91(11):2844–2850. doi: 10.1161/01.cir.91.11.2844. [DOI] [PubMed] [Google Scholar]
- Thiébaut A., Thomas X., Belhabri A., Anglaret B., Archimbaud E. Impact of pre-induction therapy leukapheresis on treatment outcome in adult acute myelogenous leukemia presenting with hyperleukocytosis. Ann Hematol. 2000 Sep;79(9):501–506. doi: 10.1007/s002770000162. [DOI] [PubMed] [Google Scholar]