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. 1984 Jun;50(3):943–946. doi: 10.1128/jvi.50.3.943-946.1984

DNA binding properties of a mutant T antigen from the simian virus 40-transformed human cell line simian virus 80.

C Gruss, E Baumann, R Knippers
PMCID: PMC255757  PMID: 6328024

Abstract

We investigated whether the T antigen of the simian virus 40-transformed human cell line simian virus 80 ( SV80 ) specifically recognizes DNA sequences of its own template, i.e, the viral sequences integrated in the SV80 cellular genome. In vitro DNA binding experiments clearly indicated that, in contrast to wild-type T antigen, SV80 T antigen does not specifically bind to sites on the integrated viral DNA in SV80 cells.

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Selected References

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