Skip to main content
Journal of Virology logoLink to Journal of Virology
. 1987 Oct;61(10):3292–3294. doi: 10.1128/jvi.61.10.3292-3294.1987

Temporal control of bovine herpesvirus 1 glycoprotein synthesis.

G V Ludwig, G J Letchworth 3rd
PMCID: PMC255911  PMID: 2442412

Abstract

The gI, gIII, and gIV glycoproteins are major bovine herpesvirus 1 antigens involved in virus neutralization. Results indicate that the gI and gIV glycoproteins were expressed as beta proteins, whereas the gIII glycoprotein was expressed strictly as a gamma protein. These findings suggest that gI and gIV may be superior to gIII as vaccine candidates.

Full text

PDF
3292

Images in this article

Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. Burkhardt E., Paulsen J. Nachweis von Bovinem Herpesvirus 1 (IBR/IPV) bei Rindern mit Affektionen des Verdauungstraktes. Berl Munch Tierarztl Wochenschr. 1978 Dec 15;91(24):480–482. [PubMed] [Google Scholar]
  2. Chang L. W., Zee Y. C., Pritchett R. F., Ardans A. A. Neutralizing monoclonal antibodies directed to infectious bovine rhinotracheitis virus. Arch Virol. 1986;88(3-4):203–215. doi: 10.1007/BF01310875. [DOI] [PubMed] [Google Scholar]
  3. Collins J. K., Butcher A. C., Riegel C. A. Immune response to bovine herpes herpesvirus type 1 infections: virus-specific antibodies in sera from infected animals. J Clin Microbiol. 1985 Apr;21(4):546–552. doi: 10.1128/jcm.21.4.546-552.1985. [DOI] [PMC free article] [PubMed] [Google Scholar]
  4. Collins J. K., Butcher A. C., Riegel C. A., McGrane V., Blair C. D., Teramoto Y. A., Winston S. Neutralizing determinants defined by monoclonal antibodies on polypeptides specified by bovine herpesvirus 1. J Virol. 1984 Nov;52(2):403–409. doi: 10.1128/jvi.52.2.403-409.1984. [DOI] [PMC free article] [PubMed] [Google Scholar]
  5. Gregersen J. P., Pauli G., Ludwig H. Bovine herpesvirus 1: differentiation of IBR- and IPV-viruses and identification and functional role of their major immunogenic components. Arch Virol. 1985;84(1-2):91–103. doi: 10.1007/BF01310556. [DOI] [PubMed] [Google Scholar]
  6. Honess R. W., Roizman B. Regulation of herpesvirus macromolecular synthesis. I. Cascade regulation of the synthesis of three groups of viral proteins. J Virol. 1974 Jul;14(1):8–19. doi: 10.1128/jvi.14.1.8-19.1974. [DOI] [PMC free article] [PubMed] [Google Scholar]
  7. Honess R. W., Roizman B. Regulation of herpesvirus macromolecular synthesis: sequential transition of polypeptide synthesis requires functional viral polypeptides. Proc Natl Acad Sci U S A. 1975 Apr;72(4):1276–1280. doi: 10.1073/pnas.72.4.1276. [DOI] [PMC free article] [PubMed] [Google Scholar]
  8. KENDRICK J. W., GILLESPIE J. H., MCENTEE K. Infectious pustular vulvovaginitis of cattle. Cornell Vet. 1958 Oct;48(4):458–495. [PubMed] [Google Scholar]
  9. Lawrence W. C., D'urso R. C., Kundel C. A., Whitbeck J. C., Bello L. J. Map location of the gene for a 130,000-dalton glycoprotein of bovine herpesvirus 1. J Virol. 1986 Nov;60(2):405–414. doi: 10.1128/jvi.60.2.405-414.1986. [DOI] [PMC free article] [PubMed] [Google Scholar]
  10. MCKERCHER D. G., WADA E. M. THE VIRUS OF INFECTIOUS BOVINE RHINOTRACHEITIS AS A CAUSE OF ABORTION IN CATTLE. J Am Vet Med Assoc. 1964 Jan 15;144:136–142. [PubMed] [Google Scholar]
  11. Marshall R. L., Rodriguez L. L., Letchworth G. J., 3rd Characterization of envelope proteins of infectious bovine rhinotracheitis virus (bovine herpesvirus 1) by biochemical and immunological methods. J Virol. 1986 Mar;57(3):745–753. doi: 10.1128/jvi.57.3.745-753.1986. [DOI] [PMC free article] [PubMed] [Google Scholar]
  12. McKercher D. G., Bibrack B., Richards W. P. Effects of the infectious bovine rhinotracheitis virus on the central nervous system of cattle. J Am Vet Med Assoc. 1970 May 15;156(10):1460–1467. [PubMed] [Google Scholar]
  13. Misra V., Blumenthal R. M., Babiuk L. A. Proteins Specified by bovine herpesvirus 1 (infectious bovine rhinotracheitis virus). J Virol. 1981 Nov;40(2):367–378. doi: 10.1128/jvi.40.2.367-378.1981. [DOI] [PMC free article] [PubMed] [Google Scholar]
  14. Misra V., Gilchrist J. E., Weinmaster G., Qualtiere L., Van den Hurk S., Babiuk L. A. Herpesvirus-induced "early" glycoprotein: characterization and possible role in immune cytolysis. J Virol. 1982 Sep;43(3):1046–1054. doi: 10.1128/jvi.43.3.1046-1054.1982. [DOI] [PMC free article] [PubMed] [Google Scholar]
  15. Okazaki K., Honda E., Minetoma T., Kumagai T. Mechanisms of neutralization by monoclonal antibodies to different antigenic sites on the bovine herpesvirus type 1 glycoproteins. Virology. 1986 Apr 15;150(1):260–264. doi: 10.1016/0042-6822(86)90285-0. [DOI] [PubMed] [Google Scholar]
  16. Okazaki K., Kawakura H., Okada M., Honda E., Minetoma T., Kumagai T. Intracellular localization and transport of three different bovine herpesvirus type 1 glycoproteins involved in neutralization. Arch Virol. 1987;92(1-2):17–26. doi: 10.1007/BF01310059. [DOI] [PubMed] [Google Scholar]
  17. STUDDERT M. J., BARKER C. A., SAVAN M. INFECTIOUS PUSTULAR VULVOVAGINITIS VIRUS INFECTION OF BULLS. Am J Vet Res. 1964 Mar;25:303–314. [PubMed] [Google Scholar]
  18. Thomson R. G. A perspective on respiratory disease in feedlot cattle. Can Vet J. 1980 Jun;21(6):181–185. [PMC free article] [PubMed] [Google Scholar]
  19. Yates W. D. A review of infectious bovine rhinotracheitis, shipping fever pneumonia and viral-bacterial synergism in respiratory disease of cattle. Can J Comp Med. 1982 Jul;46(3):225–263. [PMC free article] [PubMed] [Google Scholar]
  20. van Drunen Littel-van den Hurk S., Babiuk L. A. Antigenic and immunogenic characteristics of bovine herpesvirus type-1 glycoproteins GVP 3/9 and GVP 6/11a/16, purified by immunoadsorbent chromatography. Virology. 1985 Jul 15;144(1):204–215. doi: 10.1016/0042-6822(85)90318-6. [DOI] [PubMed] [Google Scholar]
  21. van Drunen Littel-van den Hurk S., Babiuk L. A. Effect of tunicamycin and monensin on biosynthesis, transport, and maturation of bovine herpesvirus type-1 glycoproteins. Virology. 1985 May;143(1):104–118. doi: 10.1016/0042-6822(85)90100-X. [DOI] [PMC free article] [PubMed] [Google Scholar]
  22. van Drunen Littel-van den Hurk S., Babiuk L. A. Polypeptide specificity of the antibody response after primary and recurrent infection with bovine herpesvirus 1. J Clin Microbiol. 1986 Feb;23(2):274–282. doi: 10.1128/jcm.23.2.274-282.1986. [DOI] [PMC free article] [PubMed] [Google Scholar]
  23. van Drunen Littel-van den Hurk S., Babiuk L. A. Synthesis and processing of bovine herpesvirus 1 glycoproteins. J Virol. 1986 Aug;59(2):401–410. doi: 10.1128/jvi.59.2.401-410.1986. [DOI] [PMC free article] [PubMed] [Google Scholar]
  24. van Drunen Littel-van den Hurk S., van den Hurk J. V., Babiuk L. A. Topographical analysis of bovine herpesvirus type-1 glycoproteins: use of monoclonal antibodies to identify and characterize functional epitopes. Virology. 1985 Jul 15;144(1):216–227. doi: 10.1016/0042-6822(85)90319-8. [DOI] [PubMed] [Google Scholar]
  25. van Drunen Littel-van den Hurk S., van den Hurk J. V., Gilchrist J. E., Misra V., Babiuk L. A. Interactions of monoclonal antibodies and bovine herpesvirus type 1 (BHV-1) glycoproteins: characterization of their biochemical and immunological properties. Virology. 1984 Jun;135(2):466–479. doi: 10.1016/0042-6822(84)90201-0. [DOI] [PubMed] [Google Scholar]

Articles from Journal of Virology are provided here courtesy of American Society for Microbiology (ASM)

RESOURCES