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. 1987 Dec;61(12):4023–4025. doi: 10.1128/jvi.61.12.4023-4025.1987

Map location of the thymidine kinase gene of bovine herpesvirus 1.

L J Bello 1, J C Whitbeck 1, W C Lawrence 1
PMCID: PMC256025  PMID: 2824831

Abstract

Bovine herpesvirus 1 has been reported to contain a thymidine kinase (tk) gene which is nonessential for virus replication. We have isolated a thymidine kinase-negative mutant of the virus and localized the mutation by marker rescue experiments to a 1.1-kilobase BglII-SalI fragment which maps at 0.47 to 0.48 on the bovine herpesvirus 1 genomic map. A thymidine kinase-negative bovine cell line isolated in our laboratory was used in these studies.

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Selected References

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