Abstract
During the period of January 1, 1957 to January 1, 1982, complete inpatient and outpatient records of 62 cases of synchronous cancers of the gastrointestinal tract were submitted for a retrospective analysis. The total number of gastrointestinal cancer cases from the Saint Francis General Hospital and two affiliating hospitals was 1,550 with a resultant synchronous cancer incidence of 4 percent. In this small series of 62 cases, the operability rate was 100 percent, with a resectability rate of 96 percent. The surgical morbidity and mortality rates were 12 percent and 3.2 percent, respectively.
The most frequent clinical manifestations were pain, borborygmi, nausea, vomiting, food intolerance, dysphagia, hematemesis, rectal bleeding, and weight loss.
The five and ten year survival in the synchronous group was 82 percent and 64 percent, respectively, as compared with 36.1 percent and 27.8 percent for the single malignant group.
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Selected References
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- Anderson D. E. Familial cancer and cancer families. Semin Oncol. 1978 Mar;5(1):11–16. [PubMed] [Google Scholar]
- Bargen J. A., Rankin F. W. MULTIPLE CARCINOMATA OF THE LARGE INTESTINE. Ann Surg. 1930 Apr;91(4):583–593. doi: 10.1097/00000658-193004000-00013. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Ekelund G. R., Pihl B. Mutiple carcinomas of the colon and rectum. Cancer. 1974 Jun;33(6):1630–1634. doi: 10.1002/1097-0142(197406)33:6<1630::aid-cncr2820330624>3.0.co;2-0. [DOI] [PubMed] [Google Scholar]
- Gaskin H. S., Hardy R. E., Fletcher R. L. Multiple primary malignancies in black patients. J Natl Med Assoc. 1981 Nov;73(11):1065–1068. [PMC free article] [PubMed] [Google Scholar]
- Heald R. J., Bussey H. J. Clinical experiences at St. Mark's Hospital with multiple synchronous cancers of the colon and rectum. Dis Colon Rectum. 1975 Jan-Feb;18(1):6–10. doi: 10.1007/BF02587230. [DOI] [PubMed] [Google Scholar]
- Lasser A. Synchronous primary adenocarcinomas of the colon and rectum. Dis Colon Rectum. 1978 Jan-Feb;21(1):20–22. doi: 10.1007/BF02586540. [DOI] [PubMed] [Google Scholar]
- MOERTEL C. G., BARGEN J. A., DOCKERTY M. B. Multiple carcinomas of the large intestine: a review of the literature and a study of 261 cases. Gastroenterology. 1958 Jan;34(1):85–98. [PubMed] [Google Scholar]
- MOERTEL C. G., BARGEN J. A., SOULE E. H. Multiple gastric cancers; review of the literature and study of 42 cases. Gastroenterology. 1957 Jun;32(6):1095–1103. [PubMed] [Google Scholar]
- MOERTEL C. G. INCIDENCE AND SIGNIFICANCE OF MULTIPLE PRIMARY MALIGNANT NEOPLASMS. Ann N Y Acad Sci. 1964 Apr 2;114:886–895. [PubMed] [Google Scholar]
- Patel R. M., DeSota-LaPaix F., Sika J. V., Mallaiah L. R., Purow E. Granular cell tumor of the esophagus. Am J Gastroenterol. 1981 Dec;76(6):519–523. [PubMed] [Google Scholar]
- Welch J. P. Multiple colorectal tumors. An appraisal of natural history and therapeutic options. Am J Surg. 1981 Aug;142(2):274–280. doi: 10.1016/0002-9610(81)90292-0. [DOI] [PubMed] [Google Scholar]