Abstract
A number of field isolates of avian reovirus were characterized by analysis of the migration pattern of their genomic double-stranded RNA (dsRNA) segments upon polyacrylamide gel electrophoresis. Comparison of the various isolates has demonstrated (i) no relationship between serotype and migration of any individual dsRNA segment, (ii) marked polymorphism of migration patterns of all dsRNA segments among isolates of the same serotype as well as among different serotypes, (iii) no correlation between genotype and disease state, (iv) less marked variability in migration pattern from isolates within a restricted geographic locale compared to isolates from distant locales, (v) the presence of a single genotype in local outbreaks of disease, and (vi) the relative invariant migration of several dsRNA segments among the avian reoviruses, one of which (S1) may serve to distinguish the avian from the mammalian reoviruses.
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Selected References
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- Cross R. K., Fields B. N. Reovirus-specific polypeptides: analysis using discontinuous gel electrophoresis. J Virol. 1976 Jul;19(1):162–173. doi: 10.1128/jvi.19.1.162-173.1976. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Deshmukh D. R., Pomeroy B. S. Avian reoviruses. I. Isolation and serological characterization. Avian Dis. 1969 May;13(2):239–243. [PubMed] [Google Scholar]
- Espejo R. T., Muñz O., Serafin F., Romero P. Shift in the prevalent human rotavirus detected by ribonucleic acid segment differences. Infect Immun. 1980 Feb;27(2):351–354. doi: 10.1128/iai.27.2.351-354.1980. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Fahey J. E., Crawley J. F. Studies On Chronic Respiratory Disease Of Chickens II. Isolation of A Virus. Can J Comp Med Vet Sci. 1954 Jan;18(1):13–21. [PMC free article] [PubMed] [Google Scholar]
- Glass S. E., Naqi S. A., Hall C. F., Kerr K. M. Isolation and characterization of a virus associated with arthritis of chickens. Avian Dis. 1973 Apr-Jun;17(2):415–424. [PubMed] [Google Scholar]
- Hrdy D. B., Rosen L., Fields B. N. Polymorphism of the migration of double-stranded RNA genome segments of reovirus isolates from humans, cattle, and mice. J Virol. 1979 Jul;31(1):104–111. doi: 10.1128/jvi.31.1.104-111.1979. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Johnson D. C., Van der Heide L. Incidence of tenosynovitis in Maine broilers. Avian Dis. 1971 Oct-Dec;15(4):829–834. [PubMed] [Google Scholar]
- Jones R. C., Onunkwo O. Studies on experimental tenosynovitis in light hybrid chickens. Avian Pathol. 1978 Jan;7(1):171–181. doi: 10.1080/03079457808418268. [DOI] [PubMed] [Google Scholar]
- Kalica A. R., Sereno M. M., Wyatt R. G., Mebus C. A., Chanock R. M., Kapikian A. Z. Comparison of human and animal rotavirus strains by gel electrophoresis of viral RNA. Virology. 1978 Jun 15;87(2):247–255. doi: 10.1016/0042-6822(78)90130-7. [DOI] [PubMed] [Google Scholar]
- Kawamura H., Tsubahara H. Common antigenicity of avian reoviruses. Natl Inst Anim Health Q (Tokyo) 1966 Winter;6(4):187–193. [PubMed] [Google Scholar]
- Lee P. W., Hayes E. C., Joklik W. K. Protein sigma 1 is the reovirus cell attachment protein. Virology. 1981 Jan 15;108(1):156–163. doi: 10.1016/0042-6822(81)90535-3. [DOI] [PubMed] [Google Scholar]
- Macdonald J. W., Randall C. J., Dagless M. D., McMartin D. A. Observations on viral tenosynovitis (viral arthritis) in Scotland. Avian Pathol. 1978 Oct;7(4):471–482. doi: 10.1080/03079457808418303. [DOI] [PubMed] [Google Scholar]
- Martinson H. G., Lewandowski L. J. Sequence homology studies between the double-stranded RNA genomes of cytoplasmic polyhedrosis virus, wound tumor virus, and reovirus strains 1, 2 and 3. Intervirology. 1974;4(2):91–98. doi: 10.1159/000149847. [DOI] [PubMed] [Google Scholar]
- Mustoe T. A., Ramig R. F., Sharpe A. H., Fields B. N. Genetics of reovirus: identification of the ds RNA segments encoding the polypeptides of the mu and sigma size classes. Virology. 1978 Sep;89(2):594–604. doi: 10.1016/0042-6822(78)90200-3. [DOI] [PubMed] [Google Scholar]
- Olson N. O., Solomon D. P. A natural outbreak of synovitis caused by the viral arthritis agent. Avian Dis. 1968 May;12(2):311–316. [PubMed] [Google Scholar]
- Petek M., Felluga B., Borghi G., Baroni A. The Crawley agent: an avian reovirus. Arch Gesamte Virusforsch. 1967;21(3):413–424. doi: 10.1007/BF01241740. [DOI] [PubMed] [Google Scholar]
- Rubin D. H., Fields B. N. Molecular basis of reovirus virulence. Role of the M2 gene. J Exp Med. 1980 Oct 1;152(4):853–868. doi: 10.1084/jem.152.4.853. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Sahu S. P., Olson N. O. Comparison of the characteristics of avian reoviruses isolated from the digestive and respiratory tract, with viruses isolated from the synovia. Am J Vet Res. 1975 Jun;36(6):847–850. [PubMed] [Google Scholar]
- Sharpe A. H., Fields B. N. Reovirus inhibition of cellular DNA synthesis: role of the S1 gene. J Virol. 1981 Apr;38(1):389–392. doi: 10.1128/jvi.38.1.389-392.1981. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Sharpe A. H., Ramig R. F., Mustoe T. A., Fields B. N. A genetic map of reovirus. 1. Correlation of genome RNAs between serotypes 1, 2, and 3. Virology. 1978 Jan;84(1):63–74. doi: 10.1016/0042-6822(78)90218-0. [DOI] [PubMed] [Google Scholar]
- Shatkin A. J., Sipe J. D., Loh P. Separation of ten reovirus genome segments by polyacrylamide gel electrophoresis. J Virol. 1968 Oct;2(10):986–991. doi: 10.1128/jvi.2.10.986-991.1968. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Silverstein S. C., Christman J. K., Acs G. The reovirus replicative cycle. Annu Rev Biochem. 1976;45:375–408. doi: 10.1146/annurev.bi.45.070176.002111. [DOI] [PubMed] [Google Scholar]
- Spandidos D. A., Graham A. F. Physical and chemical characterization of an avian reovirus. J Virol. 1976 Sep;19(3):968–976. doi: 10.1128/jvi.19.3.968-976.1976. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Van Der Heide L. Viral arthritis/tenosynovitis: a review. Avian Pathol. 1977;6(4):271–284. doi: 10.1080/03079457708418237. [DOI] [PubMed] [Google Scholar]
- Weiner H. L., Fields B. N. Neutralization of reovirus: the gene responsible for the neutralization antigen. J Exp Med. 1977 Nov 1;146(5):1305–1310. doi: 10.1084/jem.146.5.1305. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Wood G. W., Nicholas R. A., Hebert C. N., Thornton D. H. Serological comparisons of avian reoviruses. J Comp Pathol. 1980 Jan;90(1):29–38. doi: 10.1016/0021-9975(80)90025-0. [DOI] [PubMed] [Google Scholar]
- van der Heide L., Kalbac M. Infectious tenosynovitis (viral arthritis): characterization of a Connecticut viral isolant as a reovirus and evidence of viral egg transmission by reovirus-infected broiler breeders. Avian Dis. 1975 Oct-Dec;19(4):683–688. [PubMed] [Google Scholar]