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. 1982 Aug;43(2):749–752. doi: 10.1128/jvi.43.2.749-752.1982

Effects of fowlpox virus infection on lipid metabolism in cultured chicken embryo cells.

T M Buttke, L G Gafford
PMCID: PMC256179  PMID: 6287040

Abstract

Lipid biosynthesis was measured in cultured chicken embryo cells after infection with fowlpox virus. Between 24 and 72 h postinfection, fowlpox virus-infected cells incorporated less [14C]acetate and 3H2O into fatty acids and sterols than did mock-infected cells, demonstrating a virus-dependent inhibition of general lipid metabolism. Two specific effects of fowlpox virus infection were an accumulation of C-4 alkylated sterol intermediates and inhibition of monounsaturated fatty acid biosynthesis.

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Selected References

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