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Journal of Automated Methods and Management in Chemistry logoLink to Journal of Automated Methods and Management in Chemistry
. 2001;23(6):179–182. doi: 10.1155/S1463924601000220

Optimizing production of serially diluted compounds and distribution to multiple targets

Cole O Harris, Stephanie L Schweiker
PMCID: PMC2562853  PMID: 18924709

Abstract

The need for a multiple-target compound selectivity programme led to the establishment of a single robotic system that produces a compound's serial dilution and its distribution to multiple replicate assay plates. A Genesis RSP 150 integrated into a Zymate Laboratory Automation System XP produced the serial dilutions, and the subsequent replicate assay plates were produced quickly and accurately by an efficient use of the carousels and rapid plate. Currently, this process allows for the production of over 200 serial dilution assay plates in a workday.

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