Skip to main content
PMC home page
Journal of Virology logoLink to Journal of Virology
. 1982 Dec;44(3):1056–1067. doi: 10.1128/jvi.44.3.1056-1067.1982

Genetic studies of coliphage 186. I. Genes associated with phage morphogenesis.

S M Hocking, J B Egan
PMCID: PMC256366  PMID: 6757460

Abstract

In coliphage 186, 22 essential genes were defined by complementation studies with amber mutants. Eighteen genes were associated with phage morphogenesis: 11 with phage tail formation, and 7 with phage head formation. The remaining four genes are discussed in the accompanying paper (S. M. Hocking and J. B. Egan, J. Virol. 44:1068-1071, 1982).

Full text

PDF
1056

Images in this article

1063Image
on p.1063
1065Image
on p.1065

Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. Appleyard R K. Segregation of New Lysogenic Types during Growth of a Doubly Lysogenic Strain Derived from Escherichia Coli K12. Genetics. 1954 Jul;39(4):440–452. doi: 10.1093/genetics/39.4.440. [DOI] [PMC free article] [PubMed] [Google Scholar]
  2. BECKWITH J. RESTORATION OF OPERON ACTIVITY BY SUPPRESSORS. Biochim Biophys Acta. 1963 Sep 17;76:162–164. [PubMed] [Google Scholar]
  3. Baldwin R. L., Barrand P., Fritsch A., Goldthwait D. A., Jacob F. Cohesive sites on the deoxyribonucleic acids from several temperate coliphages. J Mol Biol. 1966 Jun;17(2):343–357. doi: 10.1016/s0022-2836(66)80146-8. [DOI] [PubMed] [Google Scholar]
  4. Bertani L. E., Bertani G. Genetics of P2 and related phages. Adv Genet. 1971;16:199–237. doi: 10.1016/s0065-2660(08)60359-4. [DOI] [PubMed] [Google Scholar]
  5. Bradley C., Ling O. P., Egan J. B. Isolation of phage P2-186 intervarietal hybrids and 186 insertion mutants. Mol Gen Genet. 1975 Sep 29;140(2):123–135. doi: 10.1007/BF00329780. [DOI] [PubMed] [Google Scholar]
  6. Campbell A. The steric effect in lysogenization by bacteriophage lambda. I. Lysogenization of a partially diploid strain of Escherichia coli K-12. Virology. 1965 Nov;27(3):329–339. doi: 10.1016/0042-6822(65)90112-1. [DOI] [PubMed] [Google Scholar]
  7. Casjens S., Horn T., Kaiser A. D. Head assembly steps controlled by genes F and W in bacteriophage lambda. J Mol Biol. 1972 Mar 14;64(3):551–563. doi: 10.1016/0022-2836(72)90082-4. [DOI] [PubMed] [Google Scholar]
  8. Garen A., Garen S., Wilhelm R. C. Suppressor genes for nonsense mutations. I. The Su-1, Su-2 and Su-3 genes of Escherichia coli. J Mol Biol. 1965 Nov;14(1):167–178. doi: 10.1016/s0022-2836(65)80238-8. [DOI] [PubMed] [Google Scholar]
  9. Georgopoulos C. P., Hohn B. Identification of a host protein necessary for bacteriophage morphogenesis (the groE gene product). Proc Natl Acad Sci U S A. 1978 Jan;75(1):131–135. doi: 10.1073/pnas.75.1.131. [DOI] [PMC free article] [PubMed] [Google Scholar]
  10. Hocking S. M., Egan J. B. Genetic studies of coliphage 186. II. Genes associated with phage replication and host cell lysis. J Virol. 1982 Dec;44(3):1068–1071. doi: 10.1128/jvi.44.3.1068-1071.1982. [DOI] [PMC free article] [PubMed] [Google Scholar]
  11. Kemp C. L., Howatson A. F., Siminovitch L. Electron microscopy studies of mutants of lambada bacteriophage. I. General description and quantitation of viral products. Virology. 1968 Nov;36(3):490–502. doi: 10.1016/0042-6822(68)90174-8. [DOI] [PubMed] [Google Scholar]
  12. King J. Assembly of the tail of bacteriophage T4. J Mol Biol. 1968 Mar 14;32(2):231–262. doi: 10.1016/0022-2836(68)90007-7. [DOI] [PubMed] [Google Scholar]
  13. Kül P. W., Katsura I. Morphogenesis of the tail of bacteriophage lambda. Virology. 1975 Jan;63(1):221–237. [PubMed] [Google Scholar]
  14. Lengyel J. A., Goldstein R. N., Marsh M., Calendar R. Structure of the bacteriophage P2 tail. Virology. 1974 Nov;62(1):161–174. doi: 10.1016/0042-6822(74)90312-2. [DOI] [PubMed] [Google Scholar]
  15. Lindahl G. Bacteriophage P2: replication of the chromosome requires a protein which acts only on the genome that coded for it. Virology. 1970 Oct;42(2):522–533. doi: 10.1016/0042-6822(70)90295-3. [DOI] [PubMed] [Google Scholar]
  16. Lindahl G. Characterization of conditional lethal mutants of bacteriophage P2. Mol Gen Genet. 1974 Feb 6;128(3):249–260. doi: 10.1007/BF00267114. [DOI] [PubMed] [Google Scholar]
  17. Lindahl G. On the control of transcription in bacteriophage P2. Virology. 1971 Dec;46(3):620–633. doi: 10.1016/0042-6822(71)90065-1. [DOI] [PubMed] [Google Scholar]
  18. Morse D. E., Primakoff P. Relief of polarity in E. coli by "suA". Nature. 1970 Apr 4;226(5240):28–31. doi: 10.1038/226028a0. [DOI] [PubMed] [Google Scholar]
  19. Mount D. W., Harris A. W., Fuerst C. R., Siminovitch L. Mutations in bacteriophage lambda affecting particle morphogenesis. Virology. 1968 May;35(1):134–149. doi: 10.1016/0042-6822(68)90313-9. [DOI] [PubMed] [Google Scholar]
  20. Parkinson J. S. Genetics of the left arm of the chromosome of bacteriophage lambda. Genetics. 1968 Jul;59(3):311–325. doi: 10.1093/genetics/59.3.311. [DOI] [PMC free article] [PubMed] [Google Scholar]
  21. Pruss G. J., Calendar R. Maturation of bacteriophage P2 DNA. Virology. 1978 May 15;86(2):454–467. doi: 10.1016/0042-6822(78)90085-5. [DOI] [PubMed] [Google Scholar]
  22. Sunshine M. G., Thorn M., Gibbs W., Calendar R., Kelly B. P2 phage amber mutants: characterization by use of a polarity suppressor. Virology. 1971 Dec;46(3):691–702. doi: 10.1016/0042-6822(71)90071-7. [DOI] [PubMed] [Google Scholar]
  23. Weigle J. Assembly of phage lambda in vitro. Proc Natl Acad Sci U S A. 1966 Jun;55(6):1462–1466. doi: 10.1073/pnas.55.6.1462. [DOI] [PMC free article] [PubMed] [Google Scholar]
  24. Woods W. H., Egan J. B. Prophage induction of noninducible coliphage 186. J Virol. 1974 Dec;14(6):1349–1356. doi: 10.1128/jvi.14.6.1349-1356.1974. [DOI] [PMC free article] [PubMed] [Google Scholar]
  25. Younghusband H. B., Egan J. B., Inman R. B. Characterization of the DNA from bacteriophage P2-186 hybrids and physical mapping of the 186 chromosome. Mol Gen Genet. 1975 Sep 29;140(2):101–110. doi: 10.1007/BF00329778. [DOI] [PubMed] [Google Scholar]
  26. Younghusband H. B., Inman R. B. Base sequence homologies between bacteriophage P2 and 186 DNAs. Virology. 1974 Dec;62(2):530–538. doi: 10.1016/0042-6822(74)90413-9. [DOI] [PubMed] [Google Scholar]
  27. Zweig M., Cummings D. J. Cleavage of head and tail proteins during bacteriophage T5 assembly: selective host involvement in the cleavage of a tail protein. J Mol Biol. 1973 Nov 5;80(3):505–518. doi: 10.1016/0022-2836(73)90418-x. [DOI] [PubMed] [Google Scholar]

Articles from Journal of Virology are provided here courtesy of American Society for Microbiology (ASM)

RESOURCES