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. 1983 Feb;45(2):855–858. doi: 10.1128/jvi.45.2.855-858.1983

Genetic relatedness of the genomes of equine herpesvirus types 1, 2, and 3.

J Staczek, S S Atherton, D J O'Callaghan
PMCID: PMC256479  PMID: 6300438

Abstract

Genomic DNAs of equine herpesvirus type 1 (EHV-1), EHV-2 (equine cytomegalovirus), and EHV-3 were examined by reassociation kinetic and thermal denaturation analyses to determine the extent and degree of homology among the three viral DNAs. Results of reassociation analyses indicated a limited homology among the three EHV genomes. Homologous DNA sequences equivalent to 1.8 to 3.7 megadaltons between EHV-1 and equine cytomegalovirus, 7.6 to 8.2 megadaltons between EHV-1 and EHV-3, and 1.3 to 1.9 megadaltons between equine cytomegalovirus and EHV-3 were detected. Examination by thermal denaturation of the DNA homoduplexes and heteroduplexes formed during reassociation revealed a high degree of base pairing within the duplexes, suggesting that closely related sequences may be conserved among the genomes of EHV.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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