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. 1983 Jun;46(3):1022–1026. doi: 10.1128/jvi.46.3.1022-1026.1983

Expression of a transformation-related protein (p53) in the malignant stage of Friend virus-induced diseases.

S K Ruscetti, E M Scolnick
PMCID: PMC256578  PMID: 6343627

Abstract

Stage 1 (pre-malignant) and stage 2 (malignant) cells derived from mice infected with Friend murine leukemia virus or polycythemia-inducing Friend virus complex were examined and compared for the expression of a transformation-related cellular protein, p53. Stage 2 cells were found to express high levels of p53, whereas stage 1 cells did not express detectable levels of this protein. These results indicate that p53 may be a marker for transformed cells present in the second stage of diseases induced by Friend murine leukemia virus or polycythemia-inducing Friend virus complex.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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