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. 1981 Oct;40(1):78–86. doi: 10.1128/jvi.40.1.78-86.1981

Aberrant glycoprotein mRNA synthesized by the internal deletion mutant of vesicular stomatitis virus.

R C Herman, R A Lazzarini
PMCID: PMC256597  PMID: 6270386

Abstract

The internal deletion mutant (DI-LT) derived from the heat-resistant strain of vesicular stomatitis virus synthesized an aberrant polyadenylated mRNA in vivo and in vitro. No normal glycoprotein message could be detected among the in vivo transcription products. The abnormal RNA contained a transcript of the partially deleted polymerase gene covalently linked to the 3' end of the glycoprotein message. The polyadenylate is located at the 3' end of the molecule and is most probably encoded by the remnant polymerase gene polyadenylation signal. This aberrant RNA may be synthesized because of either a failure to terminate transcription at the end of the glycoprotein gene or an inability to process an abnormal polycistronic precursor.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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