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. 1982 Jan;41(1):258–264. doi: 10.1128/jvi.41.1.258-264.1982

Production and characterization of monoclonal antibodies against the Epstein-Barr virus membrane antigen.

B C Strnad, T Schuster, R Klein, R F Hopkins 3rd, T Witmer, R H Neubauer, H Rabin
PMCID: PMC256747  PMID: 6177865

Abstract

Five murine hybridoma lines that produce monoclonal antibodies against Epstein-Barr virus membrane antigen (MA) were established. Immunoprecipitation experiments demonstrated that three of the antibodies precipitated both the 236,000 (236K) MA and the 212K MA. The other two antibodies precipitated the 86K MA. Antibodies against the 236K-212K MA and the 86K MA mediated complement-dependent cytolysis of Epstein-Barr-virus-infected cells. The antibodies against the 86K MA neutralized both the B95-8 and P3HR-1 viruses.

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Selected References

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