Skip to main content
Journal of the National Medical Association logoLink to Journal of the National Medical Association
. 1999 Jan;91(1):35–39.

Actinomyces and nocardia infections in immunocompromised and nonimmunocompromised patients.

D C Dominguez 1, S J Antony 1
PMCID: PMC2568306  PMID: 10063786

Abstract

A retrospective survey of nocardia and actinomyces infections in five local hospitals was conducted over a 3-year period in El Paso, Texas, a border city, in the southwestern United States. The medical records of 42 patients with suspected nocardiosis or actinomycosis were reviewed. One patient was diagnosed with actinomyces and 12 patients with nocardia. Microbiological data included morphologic characteristics, biochemical profile, and susceptibility testing. Predisposing factors included leukemia, renal insufficiency, renal transplant, and lymphoma. No predisposing factors were found in 67% (n = 8) of patients (including the patient with actinomycosis). Twenty-three percent (n = 3) of patients had disseminated disease without evidence of underlying disease or immunosuppression. The mortality and morbidity of these infections appeared to be low.

Full text

PDF
35

Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. Chouciño C., Goodman S. A., Greer J. P., Stein R. S., Wolff S. N., Dummer J. S. Nocardial infections in bone marrow transplant recipients. Clin Infect Dis. 1996 Nov;23(5):1012–1019. doi: 10.1093/clinids/23.5.1012. [DOI] [PubMed] [Google Scholar]
  2. Curry W. A. Human nocardiosis. A clinical review with selected case reports. Arch Intern Med. 1980 Jun;140(6):818–826. doi: 10.1001/archinte.140.6.818. [DOI] [PubMed] [Google Scholar]
  3. Farina C., Boiron P., Goglio A., Provost F. Human nocardiosis in northern Italy from 1982 to 1992. Northern Italy Collaborative Group on Nocardiosis. Scand J Infect Dis. 1995;27(1):23–27. doi: 10.3109/00365549509018968. [DOI] [PubMed] [Google Scholar]
  4. Lerner P. I. Nocardiosis. Clin Infect Dis. 1996 Jun;22(6):891–905. doi: 10.1093/clinids/22.6.891. [DOI] [PubMed] [Google Scholar]
  5. Menéndez R., Cordero P. J., Santos M., Gobernado M., Marco V. Pulmonary infection with Nocardia species: a report of 10 cases and review. Eur Respir J. 1997 Jul;10(7):1542–1546. doi: 10.1183/09031936.97.10071542. [DOI] [PubMed] [Google Scholar]
  6. Peters B. R., Saubolle M. A., Costantino J. M. Disseminated and cerebral infection due to Nocardia farcinica: diagnosis by blood culture and cure with antibiotics alone. Clin Infect Dis. 1996 Nov;23(5):1165–1167. doi: 10.1093/clinids/23.5.1165. [DOI] [PubMed] [Google Scholar]
  7. Poland G. A., Jorgensen C. R., Sarosi G. A. Nocardia asteroides pericarditis: report of a case and review of the literature. Mayo Clin Proc. 1990 Jun;65(6):819–824. doi: 10.1016/s0025-6196(12)62573-7. [DOI] [PubMed] [Google Scholar]
  8. Provost F., Laurent F., Blanc M. V., Boiron P. Transmission of nocardiosis and molecular typing of Nocardia species: a short review. Eur J Epidemiol. 1997 Feb;13(2):235–238. doi: 10.1023/a:1007324214800. [DOI] [PubMed] [Google Scholar]
  9. Stevens D. A., Pier A. C., Beaman B. L., Morozumi P. A., Lovett I. S., Houang E. T. Laboratory evaluation of an outbreak of nocardiosis in immunocompromised hosts. Am J Med. 1981 Dec;71(6):928–934. doi: 10.1016/0002-9343(81)90302-8. [DOI] [PubMed] [Google Scholar]
  10. Tokumoto J. I., Jacobs R. A. Case report: Nocardia osteomyelitis. Am J Med Sci. 1994 Jun;307(6):428–433. doi: 10.1097/00000441-199406000-00009. [DOI] [PubMed] [Google Scholar]
  11. Warren N. G. Actinomycosis, nocardiosis, and actinomycetoma. Dermatol Clin. 1996 Jan;14(1):85–95. doi: 10.1016/s0733-8635(05)70328-4. [DOI] [PubMed] [Google Scholar]
  12. Young L. S., Armstrong D., Blevins A., Lieberman P. Nocardia asteroides infection complicating neoplastic disease. Am J Med. 1971 Mar;50(3):356–367. doi: 10.1016/0002-9343(71)90224-5. [DOI] [PubMed] [Google Scholar]
  13. van Burik J. A., Hackman R. C., Nadeem S. Q., Hiemenz J. W., White M. H., Flowers M. E., Bowden R. A. Nocardiosis after bone marrow transplantation: a retrospective study. Clin Infect Dis. 1997 Jun;24(6):1154–1160. doi: 10.1086/513654. [DOI] [PubMed] [Google Scholar]

Articles from Journal of the National Medical Association are provided here courtesy of National Medical Association

RESOURCES