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Journal of the National Medical Association logoLink to Journal of the National Medical Association
. 2005 Feb;97(2):262–269.

Pediatric environmental health.

Bailus Walker Jr 1
PMCID: PMC2568784  PMID: 15712790

Abstract

The links between environmental agents, environmental conditions, and disease and disability among children are receiving increasing attention. Evidence abounds that children are more susceptible than adults to the damaging effects of environmental agents and conditions. This evidence is illuminated by the much-publicized and expanding research agenda on the prevention, recognition, diagnosis and treatment of environmentally related disease in the pediatric population. Encouragingly, advances in molecular biology and other sciences are providing important tools to aid pediatricians and other healthcare professionals in meeting the environmental health needs of children.

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Selected References

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  1. Adinolfi M. The development of the human blood-CSF-brain barrier. Dev Med Child Neurol. 1985 Aug;27(4):532–537. doi: 10.1111/j.1469-8749.1985.tb04581.x. [DOI] [PubMed] [Google Scholar]
  2. Aldridge Justin E., Seidler Frederic J., Slotkin Theodore A. Developmental exposure to chlorpyrifos elicits sex-selective alterations of serotonergic synaptic function in adulthood: critical periods and regional selectivity for effects on the serotonin transporter, receptor subtypes, and cell signaling. Environ Health Perspect. 2004 Feb;112(2):148–155. doi: 10.1289/ehp.6713. [DOI] [PMC free article] [PubMed] [Google Scholar]
  3. Arundel S. E., Kinnier-Wilson L. M. Parental occupations and cancer: a review of the literature. J Epidemiol Community Health. 1986 Mar;40(1):30–36. doi: 10.1136/jech.40.1.30. [DOI] [PMC free article] [PubMed] [Google Scholar]
  4. Berkowitz Gertrud S., Wetmur James G., Birman-Deych Elena, Obel Josephine, Lapinski Robert H., Godbold James H., Holzman Ian R., Wolff Mary S. In utero pesticide exposure, maternal paraoxonase activity, and head circumference. Environ Health Perspect. 2004 Mar;112(3):388–391. doi: 10.1289/ehp.6414. [DOI] [PMC free article] [PubMed] [Google Scholar]
  5. Blount B. C., Silva M. J., Caudill S. P., Needham L. L., Pirkle J. L., Sampson E. J., Lucier G. W., Jackson R. J., Brock J. W. Levels of seven urinary phthalate metabolites in a human reference population. Environ Health Perspect. 2000 Oct;108(10):979–982. doi: 10.1289/ehp.00108979. [DOI] [PMC free article] [PubMed] [Google Scholar]
  6. Collman G. W., Loomis D. P., Sandler D. P. Childhood cancer mortality and radon concentration in drinking water in North Carolina. Br J Cancer. 1991 Apr;63(4):626–629. doi: 10.1038/bjc.1991.143. [DOI] [PMC free article] [PubMed] [Google Scholar]
  7. Couzin Jennifer. Quirks of fetal environment felt decades later. Science. 2002 Jun 21;296(5576):2167–2169. doi: 10.1126/science.296.5576.2167. [DOI] [PubMed] [Google Scholar]
  8. Ekbom A., Hsieh C. C., Lipworth L., Adami H. Q., Trichopoulos D. Intrauterine environment and breast cancer risk in women: a population-based study. J Natl Cancer Inst. 1997 Jan 1;89(1):71–76. doi: 10.1093/jnci/89.1.71. [DOI] [PubMed] [Google Scholar]
  9. Faustman E. M., Silbernagel S. M., Fenske R. A., Burbacher T. M., Ponce R. A. Mechanisms underlying Children's susceptibility to environmental toxicants. Environ Health Perspect. 2000 Mar;108 (Suppl 1):13–21. doi: 10.1289/ehp.00108s113. [DOI] [PMC free article] [PubMed] [Google Scholar]
  10. Funatsu I., Yamashita F., Ito Y., Tsugawa S., Funatsu T. Polychlorbiphenyls (PCB) induced fetopathy. I. Clinical observation. Kurume Med J. 1972;19(1):43–51. doi: 10.2739/kurumemedj.19.43. [DOI] [PubMed] [Google Scholar]
  11. GILES D., HEWITT D., STEWART A., WEBB J. Malignant disease in childhood and diagnostic irradiation in utero. Lancet. 1956 Sep 1;271(6940):447–447. doi: 10.1016/s0140-6736(56)91923-7. [DOI] [PubMed] [Google Scholar]
  12. Gent Janneane F., Ren Ping, Belanger Kathleen, Triche Elizabeth, Bracken Michael B., Holford Theodore R., Leaderer Brian P. Levels of household mold associated with respiratory symptoms in the first year of life in a cohort at risk for asthma. Environ Health Perspect. 2002 Dec;110(12):A781–A786. doi: 10.1289/ehp.021100781. [DOI] [PMC free article] [PubMed] [Google Scholar]
  13. Ginsberg Gary, Slikker William, Jr, Bruckner James, Sonawane Babasaheb. Incorporating children's toxicokinetics into a risk framework. Environ Health Perspect. 2004 Feb;112(2):272–283. doi: 10.1289/ehp.6013. [DOI] [PMC free article] [PubMed] [Google Scholar]
  14. Lacey D. L., Tan H. L., Lu J., Kaufman S., Van G., Qiu W., Rattan A., Scully S., Fletcher F., Juan T. Osteoprotegerin ligand modulates murine osteoclast survival in vitro and in vivo. Am J Pathol. 2000 Aug;157(2):435–448. doi: 10.1016/S0002-9440(10)64556-7. [DOI] [PMC free article] [PubMed] [Google Scholar]
  15. Lubin B., Lewis R. Biomarkers and pediatric environmental health. Environ Health Perspect. 1995 Sep;103 (Suppl 6):99–104. doi: 10.1289/ehp.95103s699. [DOI] [PMC free article] [PubMed] [Google Scholar]
  16. Pogoda J. M., Preston-Martin S. Household pesticides and risk of pediatric brain tumors. Environ Health Perspect. 1997 Nov;105(11):1214–1220. doi: 10.1289/ehp.971051214. [DOI] [PMC free article] [PubMed] [Google Scholar]
  17. Rahman F., Langford K. H., Scrimshaw M. D., Lester J. N. Polybrominated diphenyl ether (PBDE) flame retardants. Sci Total Environ. 2001 Jul 25;275(1-3):1–17. doi: 10.1016/s0048-9697(01)00852-x. [DOI] [PubMed] [Google Scholar]
  18. Roberts Rosemary, Rodriguez William, Murphy Dianne, Crescenzi Terrie. Pediatric drug labeling: improving the safety and efficacy of pediatric therapies. JAMA. 2003 Aug 20;290(7):905–911. doi: 10.1001/jama.290.7.905. [DOI] [PubMed] [Google Scholar]
  19. Savitz D. A., Chen J. H. Parental occupation and childhood cancer: review of epidemiologic studies. Environ Health Perspect. 1990 Aug;88:325–337. doi: 10.1289/ehp.9088325. [DOI] [PMC free article] [PubMed] [Google Scholar]
  20. West Daniel C., Romano Patrick S., Azari Rahman, Rudominer Andrea, Holman Mark, Sandhu Surdip. Impact of environmental tobacco smoke on children with sickle cell disease. Arch Pediatr Adolesc Med. 2003 Dec;157(12):1197–1201. doi: 10.1001/archpedi.157.12.1197. [DOI] [PubMed] [Google Scholar]
  21. Whyatt Robin M., Camann David E., Kinney Patrick L., Reyes Andria, Ramirez Judy, Dietrich Jessica, Diaz Diurka, Holmes Darrell, Perera Frederica P. Residential pesticide use during pregnancy among a cohort of urban minority women. Environ Health Perspect. 2002 May;110(5):507–514. doi: 10.1289/ehp.02110507. [DOI] [PMC free article] [PubMed] [Google Scholar]
  22. Zahm S. H., Ward M. H. Pesticides and childhood cancer. Environ Health Perspect. 1998 Jun;106 (Suppl 3):893–908. doi: 10.1289/ehp.98106893. [DOI] [PMC free article] [PubMed] [Google Scholar]

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