Abstract
Splenosis is a rare condition described as ectopic splenic tissue implantation generally after a splenic rupture. A 35-year-old male patient who had a history of splenectomy operation due to gunshot wound seven years ago was referred to our hospital with complaints, including exhaustion, sweating and shortness of breath. Thoracic computed tomography of the patient showed nodular pleural thickenings at the level of the left lower lobe, which proved to be unrelated with the presenting symptoms. The patient underwent a minithoracotomy for diagnosis and treatment. During the intraoperative observation, dark-colored, soft, multiple nodular lesions with a biggest size of 2 cm inside the visceral pleura over an area of 5 x 10 cm in dimension were observed. Also, a few tiny nodules in the lung parenchyma approximately 1-cm deep to the pleural nodules were palpated. The lesions were excised. The histopathological examination of the specimen showed splenic tissue in the lung parenchyma and pleura, so the lesions were accepted as splenosis. Pleuropulmonary splenosis, which develops generally after simultaneous rupture of the diaphragma and spleen, is a very rare condition. Most of the patients are asymptomatic and the lesions are detected accidentally. If the diagnosis can be made preoperatively, surgical excision is not needed.
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- Cordier J. F., Gamondes J. P., Marx P., Heinen I., Loire R. Thoracic splenosis presenting with hemoptysis. Chest. 1992 Aug;102(2):626–627. doi: 10.1378/chest.102.2.626. [DOI] [PubMed] [Google Scholar]
- Gaines J. J., Crosby J. H., Vinayak Kamath M. Diagnosis of thoracic splenosis by tru-cut needle biopsy. Am Rev Respir Dis. 1986 Jun;133(6):1199–1201. doi: 10.1164/arrd.1986.133.6.1199. [DOI] [PubMed] [Google Scholar]
- Gopal Karthikeyan, Jones Mark Trevor, Greaves Susan Melanie. An unusual cause of chest pain. Chest. 2004 Apr;125(4):1536–1538. doi: 10.1378/chest.125.4.1536. [DOI] [PubMed] [Google Scholar]
- Hathaway J. M., Harley R. A., Self S., Schiffman G., Virella G. Immunological function in post-traumatic splenosis. Clin Immunol Immunopathol. 1995 Feb;74(2):143–150. doi: 10.1006/clin.1995.1021. [DOI] [PubMed] [Google Scholar]
- Miller J. S., Nunez A., Espada R. Thoracic splenosis 25 years after gunshot wound to the abdomen. J Trauma. 2001 Jan;50(1):149–150. doi: 10.1097/00005373-200101000-00032. [DOI] [PubMed] [Google Scholar]
- Pearson H. A., Johnston D., Smith K. A., Touloukian R. J. The born-again spleen. Return of splenic function after splenectomy for trauma. N Engl J Med. 1978 Jun 22;298(25):1389–1392. doi: 10.1056/NEJM197806222982504. [DOI] [PubMed] [Google Scholar]
- Rickert C. H., Maasjosthusmann U., Probst-Cousin S., August C., Gullotta F. A unique case of cerebral spleen. Am J Surg Pathol. 1998 Jul;22(7):894–896. doi: 10.1097/00000478-199807000-00011. [DOI] [PubMed] [Google Scholar]
- Rubio Garay M., Belda Sanchís J., Iglesias Sentís M., Gimferrer Garolera J. M., Catalán Biel M., Callejas Pérez M. A. Diagnóstico no invasivo de la esplenosis torácica postraumática. Arch Bronconeumol. 2004 Mar;40(3):139–140. [PubMed] [Google Scholar]
- Sarda R., Sproat I., Kurtycz D. F., Hafez R. Pulmonary parenchymal splenosis. Diagn Cytopathol. 2001 May;24(5):352–355. doi: 10.1002/dc.1076. [DOI] [PubMed] [Google Scholar]
- Singh P., Munn N. J., Patel H. K. Thoracic splenosis. N Engl J Med. 1995 Sep 28;333(13):882–882. doi: 10.1056/NEJM199509283331318. [DOI] [PubMed] [Google Scholar]
- Wold Peter B., Farrell Michael A. Pleural nodularity in a patient with pyrexia of unknown origin. Chest. 2002 Aug;122(2):718–720. doi: 10.1378/chest.122.2.718. [DOI] [PubMed] [Google Scholar]
- Yammine Joseph N., Yatim Ahmad, Barbari Antoine. Radionuclide imaging in thoracic splenosis and a review of the literature. Clin Nucl Med. 2003 Feb;28(2):121–123. doi: 10.1097/01.RLU.0000048681.29894.BA. [DOI] [PubMed] [Google Scholar]


