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. 1992 May;60(5):1864–1868. doi: 10.1128/iai.60.5.1864-1868.1992

Nucleotide sequence of the ospAB operon of a Borrelia burgdorferi strain expressing OspA but not OspB.

H Eiffert 1, A Ohlenbusch 1, W Fehling 1, H Lotter 1, R Thomssen 1
PMCID: PMC257086  PMID: 1563775

Abstract

The nucleotide sequence of a 1.6-kb clone containing the gene for outer surface protein A (OspA) of a German strain (GO2) of Borrelia burgdorferi was determined. The deduced amino acid sequence showed a homology of 82% to the OspA molecules from three other B. burgdorferi strains. The best-conserved region was recognized at the 36-amino-terminal amino acids of OspA. OspB could not be identified in the strain investigated, probably because the nucleotide sequence of the ospAB operon prevented expression of the OspB gene.

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