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. 1992 May;60(5):2092–2095. doi: 10.1128/iai.60.5.2092-2095.1992

Enteroaggregative Escherichia coli strains secrete a heat-labile toxin antigenically related to E. coli hemolysin.

T J Baldwin 1, S Knutton 1, L Sellers 1, H A Hernandez 1, A Aitken 1, P H Williams 1
PMCID: PMC257119  PMID: 1563799

Abstract

A protein toxin of approximately 120,000 Da secreted by nonhemolytic enteroaggregative Escherichia coli strains cross-reacted in Western blots (immunoblots) with antibodies raised against the C-terminal region of E. coli hemolysin. Treatment of HEp-2 cells with enteroaggregative E. coli or culture supernatants caused elevation of intracellular calcium and stimulated calcium-dependent protein phosphorylation.

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Selected References

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