Skip to main content
NCBI home page
Journal of the National Medical Association logoLink to Journal of the National Medical Association
editorial
. 1986 Jul;78(7):599–600.

Therapeutic manipulation of globin gene expression in the hemoglobinopathies.

C S Johnson
PMCID: PMC2571390  PMID: 3746928

Full text

PDF
599

Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. Charache S., Dover G., Smith K., Talbot C. C., Jr, Moyer M., Boyer S. Treatment of sickle cell anemia with 5-azacytidine results in increased fetal hemoglobin production and is associated with nonrandom hypomethylation of DNA around the gamma-delta-beta-globin gene complex. Proc Natl Acad Sci U S A. 1983 Aug;80(15):4842–4846. doi: 10.1073/pnas.80.15.4842. [DOI] [PMC free article] [PubMed] [Google Scholar]
  2. Johnson F. L., Look A. T., Gockerman J., Ruggiero M. R., Dalla-Pozza L., Billings F. T., 3rd Bone-marrow transplantation in a patient with sickle-cell anemia. N Engl J Med. 1984 Sep 20;311(12):780–783. doi: 10.1056/NEJM198409203111207. [DOI] [PubMed] [Google Scholar]
  3. Letvin N. L., Linch D. C., Beardsley G. P., McIntyre K. W., Nathan D. G. Augmentation of fetal-hemoglobin production in anemic monkeys by hydroxyurea. N Engl J Med. 1984 Apr 5;310(14):869–873. doi: 10.1056/NEJM198404053101401. [DOI] [PubMed] [Google Scholar]
  4. Ley T. J., DeSimone J., Anagnou N. P., Keller G. H., Humphries R. K., Turner P. H., Young N. S., Keller P., Nienhuis A. W. 5-azacytidine selectively increases gamma-globin synthesis in a patient with beta+ thalassemia. N Engl J Med. 1982 Dec 9;307(24):1469–1475. doi: 10.1056/NEJM198212093072401. [DOI] [PubMed] [Google Scholar]
  5. Ley T. J., DeSimone J., Noguchi C. T., Turner P. H., Schechter A. N., Heller P., Nienhuis A. W. 5-Azacytidine increases gamma-globin synthesis and reduces the proportion of dense cells in patients with sickle cell anemia. Blood. 1983 Aug;62(2):370–380. [PubMed] [Google Scholar]
  6. Nash G. B., Johnson C. S., Meiselman H. J. Mechanical properties of oxygenated red blood cells in sickle cell (HbSS) disease. Blood. 1984 Jan;63(1):73–82. [PubMed] [Google Scholar]
  7. Razin A., Riggs A. D. DNA methylation and gene function. Science. 1980 Nov 7;210(4470):604–610. doi: 10.1126/science.6254144. [DOI] [PubMed] [Google Scholar]
  8. Smith C. M., 2nd, Krivit W., White J. G. The irreversibly sickled cell. Am J Pediatr Hematol Oncol. 1982 Fall;4(3):307–315. [PubMed] [Google Scholar]
  9. Thomas E. D., Buckner C. D., Sanders J. E., Papayannopoulou T., Borgna-Pignatti C., De Stefano P., Sullivan K. M., Clift R. A., Storb R. Marrow transplantation for thalassaemia. Lancet. 1982 Jul 31;2(8292):227–229. doi: 10.1016/s0140-6736(82)90319-1. [DOI] [PubMed] [Google Scholar]
  10. Thomas E. D. Marrow transplantation for nonmalignant disorders. N Engl J Med. 1985 Jan 3;312(1):46–48. doi: 10.1056/NEJM198501033120110. [DOI] [PubMed] [Google Scholar]
  11. Torrealba-de Ron A. T., Papayannopoulou T., Knapp M. S., Fu M. F., Knitter G., Stamatoyannopoulos G. Perturbations in the erythroid marrow progenitor cell pools may play a role in the augmentation of HbF by 5-azacytidine. Blood. 1984 Jan;63(1):201–210. [PubMed] [Google Scholar]
  12. Wood W. G., Pembrey M. E., Serjeant G. R., Perrine R. P., Weatherall D. J. Hb F synthesis in sickle cell anaemia: a comparison of Saudi Arab cases with those of African origin. Br J Haematol. 1980 Jul;45(3):431–445. doi: 10.1111/j.1365-2141.1980.tb07163.x. [DOI] [PubMed] [Google Scholar]

Articles from Journal of the National Medical Association are provided here courtesy of National Medical Association

RESOURCES