Skip to main content
PMC home page
Infection and Immunity logoLink to Infection and Immunity
. 1992 Jul;60(7):3015–3016. doi: 10.1128/iai.60.7.3015-3016.1992

Characterization of GP110, a neutrophil surface protein.

S C Tripathi 1, T E Van Dyke 1
PMCID: PMC257270  PMID: 1612770

Abstract

Localized juvenile periodontosis is associated with a defect of neutrophil chemotaxis that is characterized by selective depletion of a surface protein with a molecular mass of 110 kDa (GP110). Data on partial characterization of GP110 suggest that it is a glycoprotein which is enriched in Lys, Glu, His, Leu, and Ala residues.

Full text

PDF
3015

Images in this article

3016Image
on p.3016

Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. Baer P. N. The case for periodontosis as a clinical entity. J Periodontol. 1971 Aug;42(8):516–520. doi: 10.1902/jop.1971.42.8.516. [DOI] [PubMed] [Google Scholar]
  2. Cainciola L. J., Genco R. J., Patters M. R., McKenna J., van Oss C. J. Defective polymorphonuclear leukocyte function in a human periodontal disease. Nature. 1977 Feb 3;265(5593):445–447. doi: 10.1038/265445a0. [DOI] [PubMed] [Google Scholar]
  3. Clark R. A., Page R. C., Wilde G. Defective neutrophil chemotaxis in juvenile periodontitis. Infect Immun. 1977 Dec;18(3):694–700. doi: 10.1128/iai.18.3.694-700.1977. [DOI] [PMC free article] [PubMed] [Google Scholar]
  4. Corbi A. L., Miller L. J., O'Connor K., Larson R. S., Springer T. A. cDNA cloning and complete primary structure of the alpha subunit of a leukocyte adhesion glycoprotein, p150,95. EMBO J. 1987 Dec 20;6(13):4023–4028. doi: 10.1002/j.1460-2075.1987.tb02746.x. [DOI] [PMC free article] [PubMed] [Google Scholar]
  5. Cotter T. G., Henson P. M. A cell surface differentiation antigen involved in human neutrophil chemotaxis and degranulation. Clin Exp Immunol. 1983 Jul;53(1):249–253. [PMC free article] [PubMed] [Google Scholar]
  6. Cotter T. G., Henson P. M. Purification and characterization of an antigen involved in neutrophil chemotaxis and degranulation using a monoclonal antibody. Eur J Immunol. 1984 Jul;14(7):605–609. doi: 10.1002/eji.1830140705. [DOI] [PubMed] [Google Scholar]
  7. Cotter T. G., Spears P., Henson P. M. A monoclonal antibody inhibiting human neutrophil chemotaxis and degranulation. J Immunol. 1981 Oct;127(4):1355–1360. [PubMed] [Google Scholar]
  8. Kishimoto T. K., O'Connor K., Lee A., Roberts T. M., Springer T. A. Cloning of the beta subunit of the leukocyte adhesion proteins: homology to an extracellular matrix receptor defines a novel supergene family. Cell. 1987 Feb 27;48(4):681–690. doi: 10.1016/0092-8674(87)90246-7. [DOI] [PubMed] [Google Scholar]
  9. Lavine W. S., Maderazo E. G., Stolman J., Ward P. A., Cogen R. B., Greenblatt I., Robertson P. B. Impaired neutrophil chemotaxis in patients with juvenile and rapidly progressing periodontitis. J Periodontal Res. 1979 Jan;14(1):10–19. doi: 10.1111/j.1600-0765.1979.tb00213.x. [DOI] [PubMed] [Google Scholar]
  10. Melnick M., Shields E. D., Bixler D. Periodontosis: a phenotypic and genetic analysis. Oral Surg Oral Med Oral Pathol. 1976 Jul;42(1):32–41. doi: 10.1016/0030-4220(76)90029-3. [DOI] [PubMed] [Google Scholar]
  11. Saxén L., Nevanlinna H. R. Autosomal recessive inheritance of juvenile periodontitis: test of a hypothesis. Clin Genet. 1984 Apr;25(4):332–335. doi: 10.1111/j.1399-0004.1984.tb01999.x. [DOI] [PubMed] [Google Scholar]
  12. Suzuki J. B., Collison B. C., Falkler W. A., Jr, Nauman R. K. Immunologic profile of juvenile periodontitis. II. Neutrophil chemotaxis, phagocytosis and spore germination. J Periodontol. 1984 Aug;55(8):461–467. doi: 10.1902/jop.1984.55.8.461. [DOI] [PubMed] [Google Scholar]
  13. Van Dyke T. E., Horoszewicz H. U., Cianciola L. J., Genco R. J. Neutrophil chemotaxis dysfunction in human periodontitis. Infect Immun. 1980 Jan;27(1):124–132. doi: 10.1128/iai.27.1.124-132.1980. [DOI] [PMC free article] [PubMed] [Google Scholar]
  14. Van Dyke T. E., Horoszewicz H. U., Genco R. J. The polymorphonuclear leukocyte (PMNL) locomotor defect in juvenile periodontitis. Study of random migration, chemokinesis and chemotaxis. J Periodontol. 1982 Nov;53(11):682–687. doi: 10.1902/jop.1982.53.11.682. [DOI] [PubMed] [Google Scholar]
  15. Van Dyke T. E., Schweinebraten M., Cianciola L. J., Offenbacher S., Genco R. J. Neutrophil chemotaxis in families with localized juvenile periodontitis. J Periodontal Res. 1985 Sep;20(5):503–514. doi: 10.1111/j.1600-0765.1985.tb00834.x. [DOI] [PubMed] [Google Scholar]
  16. Van Dyke T. E., Wilson-Burrows C., Offenbacher S., Henson P. Association of an abnormality of neutrophil chemotaxis in human periodontal disease with a cell surface protein. Infect Immun. 1987 Sep;55(9):2262–2267. doi: 10.1128/iai.55.9.2262-2267.1987. [DOI] [PMC free article] [PubMed] [Google Scholar]
  17. Wright J. T., Elmer W. A., Dunlop A. T. A simple method for plasma membrane isolation from embryonic tissue using positively charged microcarriers. Anal Biochem. 1982 Sep 1;125(1):100–104. doi: 10.1016/0003-2697(82)90388-8. [DOI] [PubMed] [Google Scholar]

Articles from Infection and Immunity are provided here courtesy of American Society for Microbiology (ASM)

RESOURCES