Table 1.
Clinical and Demographic Characteristics of Patients
| Patient | Sex | Age | Age at onset, years |
SP | HH | AB | DNS | Therapy withdraw one month before admission, daily dose | Therapy at PSG time, daily dose | ||
|---|---|---|---|---|---|---|---|---|---|---|---|
| EDS | Cataplexy | RBD | |||||||||
| 1 | M | 36 | 10 | 18 | − | + | + | + | + | Valproic Acid 1,250 mg; Citalopram 20 mg | |
| 2 | M | 41 | 33 | 33 | − | + | − | − | + | drug naive | |
| 3 | F | 52 | 49 | 50 | − | − | − | − | − | Paroxetine 20 mg | |
| 4 | M | 35 | 13 | 15 | − | − | − | − | + | drug naive | |
| 5 | M | 44 | 33 | 33 | − | + | + | + | + | drug naive | |
| 6 | F | 33 | 18 | n.a. | − | + | + | + | − | drug naive | |
| 7 | F | 20 | 12 | 12 | − | + | + | − | + | drug naive | |
| 8 | F | 73 | 45 | 44 | − | − | − | − | + | Enalapril 10 mg | Thyroxine sodium 50 mg; Furosemide 25 mg |
| 9 | F | 18 | 10 | 16 | − | + | + | + | − | Modafinil 100 mg | |
| 10 | F | 23 | 9 | 22 | − | − | + | − | + | drug naive | |
| 11 | M | 31 | 18 | 18 | − | − | − | + | − | drug naive | |
| 12 | F | 37 | 29 | 29 | − | + | + | + | + | Modafinil 100 mg; Venlafaxine 75 mg | |
| 13 | M | 59 | 48 | n.a. | − | − | − | − | − | Fluoxetine 60 mg | |
| 14 | M | 67 | 13 | 13 | − | − | − | + | + | drug naive | Nifedipine 40 mg; Perindopril 2 mg |
| 15 | M | 44 | 40 | n.a. | − | − | − | − | − | drug naive | |
| 16 | M | 35 | 15 | 15 | − | + | − | − | + | drug naive | |
| 17 | F | 34 | 19 | 19 | − | + | + | − | + | drug naive | |
| 18 | M | 66 | 10 | 40 | 50 | − | − | − | − | Sertraline 50 mg; Flurazepam 15 mg | Metformin 500 mg; Alfuzosin 10 mg |
| 19 | F | 36 | 24 | 24 | 24 | + | + | − | + | drug naive | |
| 20 | M | 25 | 10 | 10 | 15 | − | − | + | + | Imipramine 30 mg | |
| 21 | M | 32 | 11 | 11 | 12 | − | + | − | − | Modafinil 100 mg | |
| 22 | F | 41 | 15 | 16 | 20 | − | + | + | + | Modafinil 100 mg | |
| 23 | F | 59 | 45 | 47 | 50 | + | + | + | + | Modafinil 200 mg; Clomipramine 50 mg | |
| 24 | M | 75 | 18 | 20 | 22 | − | − | − | + | Modafinil 100 mg | |
| 25 | M | 31 | 15 | 26 | 28 | + | + | + | + | drug naive | |
| 26 | M | 55 | 44 | 44 | 50 | − | + | + | + | drug naive | |
| 27 | M | 38 | 17 | 20 | 20 | + | + | + | + | drug naive | |
| 28 | M | 24 | 7 | n.a. | 16 | − | − | − | − | drug naive | |
| 29 | M | 44 | 22 | 22 | 19 | − | + | + | + | drug naive | |
| 30 | M | 50 | 16 | 15 | 18 | − | + | − | + | drug naive | |
| 31 | M | 30 | 18 | 20 | 24 | + | + | + | + | Modafinil 200 mg | |
| 32 | F | 35 | 14 | 14 | 25 | + | + | + | − | drug naive | |
| 33 | M | 36 | 28 | n.a. | 30 | − | − | − | − | drug naive | |
| 34 | M | 20 | 18 | 19 | 19 | − | − | − | − | drug naive | |
EDS = Excessive daytime sleepiness; SP = sleep paralysis; HH = hypnagogic/hypnopompic hallucinations; AB = automatic behaviors; DNS = disturbed nocturnal sleep; n.a. = not available; + = present; − = absent.