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Journal of the National Medical Association logoLink to Journal of the National Medical Association
. 2006 Mar;98(3):430–435.

National patterns of dementia treatment among elderly ambulatory patients.

Mary K Maneno 1, Euni Lee 1, Anthony K Wutoh 1, Ilene H Zuckerman 1, Patrice Jackson 1, Fredric A Lombardo 1, Kenneth R Scott 1, Zhenyi Xue 1
PMCID: PMC2576124  PMID: 16573310

Abstract

PURPOSES: To assess patterns of dementia/Alzheimer's disease (AD) management and to investigate predictive factors of cholinesterase inhibitor prescriptions. METHODOLOGY: A cross-sectional study was conducted using a national survey among the elderly aged >60 from 2000 to 2002. Visit characteristics and cholinesterase inhibitor prescriptions associated with dementia/AD status were evaluated. MAIN FINDINGS: A total of 25,561 visit records were identified. Of the total visits, only 0.6% had dementia/AD records. Most of the dementia/AD visits were made by women (60.6%) and white patients (93.5%). Of the dementia/AD visits, about half (46.5%) were prescribed with one or more cholinesterase inhibitors. Donepezil was the most prevalent agent (68.0%) followed by rivastigmine (26.0%). Logistic regression analyses indicated that the physician's specialty was a strong predictor for cholinesterase inhibitor prescription; psychiatrists [odds ratio (OR)=5.5; p<0.01] and neurologists (OR=2.6; p<0.03) were more likely to prescribe cholinesterase inhibitor than other physicians. Other characteristics including race did not show significant association. CONCLUSIONS: The study findings suggest that physicians who specialized in psychiatry and neurology predominantly provided ambulatory care services for dementia patients. More efforts should be given to detect and to treat dementia patients with cognitive-enhancing agents after the formal diagnosis in the ambulatory care setting.

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Selected References

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  1. Baker F. M. Ethnic minority elders: a mental health research agenda. Hosp Community Psychiatry. 1992 Apr;43(4):337-8, 342. doi: 10.1176/ps.43.4.337. [DOI] [PubMed] [Google Scholar]
  2. Baker F. M. Psychiatric treatment of older African Americans. Hosp Community Psychiatry. 1994 Jan;45(1):32–37. doi: 10.1176/ps.45.1.32. [DOI] [PubMed] [Google Scholar]
  3. Behavioral and Psychological Signs and Symptoms of Dementia: Implications for Research and Treatment. Proceedings of an international consensus conference. Lansdowne, Virginia, April 1996. Int Psychogeriatr. 1996;8 (Suppl 3):215–552. [PubMed] [Google Scholar]
  4. Callahan C. M., Hendrie H. C., Tierney W. M. Documentation and evaluation of cognitive impairment in elderly primary care patients. Ann Intern Med. 1995 Mar 15;122(6):422–429. doi: 10.7326/0003-4819-122-6-199503150-00004. [DOI] [PubMed] [Google Scholar]
  5. Doody R. S., Geldmacher D. S., Gordon B., Perdomo C. A., Pratt R. D., Donepezil Study Group Open-label, multicenter, phase 3 extension study of the safety and efficacy of donepezil in patients with Alzheimer disease. Arch Neurol. 2001 Mar;58(3):427–433. doi: 10.1001/archneur.58.3.427. [DOI] [PubMed] [Google Scholar]
  6. Doraiswamy P. M., Steffens D. C., Pitchumoni S., Tabrizi S. Early recognition of Alzheimer's disease: what is consensual? What is controversial? What is practical? J Clin Psychiatry. 1998;59 (Suppl 13):6–18. [PubMed] [Google Scholar]
  7. Drevets W. C., Rubin E. H. Psychotic symptoms and the longitudinal course of senile dementia of the Alzheimer type. Biol Psychiatry. 1989 Jan;25(1):39–48. doi: 10.1016/0006-3223(89)90145-5. [DOI] [PubMed] [Google Scholar]
  8. Gao S., Hendrie H. C., Hall K. S., Hui S. The relationships between age, sex, and the incidence of dementia and Alzheimer disease: a meta-analysis. Arch Gen Psychiatry. 1998 Sep;55(9):809–815. doi: 10.1001/archpsyc.55.9.809. [DOI] [PubMed] [Google Scholar]
  9. Griffith Veronica T. Diagnose and treat mild to moderate Alzheimer's disease. Nurse Pract. 2002 Dec;27(12):13–26. doi: 10.1097/00006205-200212000-00003. [DOI] [PubMed] [Google Scholar]
  10. Guo Z., Viitanen M., Winblad B., Fratiglioni L. Low blood pressure and incidence of dementia in a very old sample: dependent on initial cognition. J Am Geriatr Soc. 1999 Jun;47(6):723–726. doi: 10.1111/j.1532-5415.1999.tb01597.x. [DOI] [PubMed] [Google Scholar]
  11. Gurland B. J., Wilder D. E., Lantigua R., Stern Y., Chen J., Killeffer E. H., Mayeux R. Rates of dementia in three ethnoracial groups. Int J Geriatr Psychiatry. 1999 Jun;14(6):481–493. [PubMed] [Google Scholar]
  12. Hendrie H. C. Epidemiology of dementia and Alzheimer's disease. Am J Geriatr Psychiatry. 1998 Spring;6(2 Suppl 1):S3–18. doi: 10.1097/00019442-199821001-00002. [DOI] [PubMed] [Google Scholar]
  13. Heyman A., Fillenbaum G., Prosnitz B., Raiford K., Burchett B., Clark C. Estimated prevalence of dementia among elderly black and white community residents. Arch Neurol. 1991 Jun;48(6):594–598. doi: 10.1001/archneur.1991.00530180046016. [DOI] [PubMed] [Google Scholar]
  14. Husaini Baqar A., Sherkat Darren E., Moonis Majaz, Levine Robert, Holzer Charles, Cain Van A. Racial differences in the diagnosis of dementia and in its effects on the use and costs of health care services. Psychiatr Serv. 2003 Jan;54(1):92–96. doi: 10.1176/appi.ps.54.1.92. [DOI] [PubMed] [Google Scholar]
  15. Iwase S., Mano T., Watanabe T., Saito M., Kobayashi F. Age-related changes of sympathetic outflow to muscles in humans. J Gerontol. 1991 Jan;46(1):M1–M5. doi: 10.1093/geronj/46.1.m1. [DOI] [PubMed] [Google Scholar]
  16. Lasser Karen E., Himmelstein David U., Woolhandler Steffie J., McCormick Danny, Bor David H. Do minorities in the United States receive fewer mental health services than whites? Int J Health Serv. 2002;32(3):567–578. doi: 10.2190/UEXW-RARL-U46V-FU4P. [DOI] [PubMed] [Google Scholar]
  17. Mega M. S., Cummings J. L., Fiorello T., Gornbein J. The spectrum of behavioral changes in Alzheimer's disease. Neurology. 1996 Jan;46(1):130–135. doi: 10.1212/wnl.46.1.130. [DOI] [PubMed] [Google Scholar]
  18. Olfson M., Klerman G. L. The treatment of depression: prescribing practices of primary care physicians and psychiatrists. J Fam Pract. 1992 Dec;35(6):627–635. [PubMed] [Google Scholar]
  19. Olfson M., Pincus H. A. Outpatient psychotherapy in the United States, I: Volume, costs, and user characteristics. Am J Psychiatry. 1994 Sep;151(9):1281–1288. doi: 10.1176/ajp.151.9.1281. [DOI] [PubMed] [Google Scholar]
  20. Perkins P., Annegers J. F., Doody R. S., Cooke N., Aday L., Vernon S. W. Incidence and prevalence of dementia in a multiethnic cohort of municipal retirees. Neurology. 1997 Jul;49(1):44–50. doi: 10.1212/wnl.49.1.44. [DOI] [PubMed] [Google Scholar]
  21. Richards S. S., Hendrie H. C. Diagnosis, management, and treatment of Alzheimer disease: a guide for the internist. Arch Intern Med. 1999 Apr 26;159(8):789–798. doi: 10.1001/archinte.159.8.789. [DOI] [PubMed] [Google Scholar]
  22. Rösler M., Anand R., Cicin-Sain A., Gauthier S., Agid Y., Dal-Bianco P., Stähelin H. B., Hartman R., Gharabawi M. Efficacy and safety of rivastigmine in patients with Alzheimer's disease: international randomised controlled trial. BMJ. 1999 Mar 6;318(7184):633–638. doi: 10.1136/bmj.318.7184.633. [DOI] [PMC free article] [PubMed] [Google Scholar]
  23. Small G. W., Rabins P. V., Barry P. P., Buckholtz N. S., DeKosky S. T., Ferris S. H., Finkel S. I., Gwyther L. P., Khachaturian Z. S., Lebowitz B. D. Diagnosis and treatment of Alzheimer disease and related disorders. Consensus statement of the American Association for Geriatric Psychiatry, the Alzheimer's Association, and the American Geriatrics Society. JAMA. 1997 Oct 22;278(16):1363–1371. [PubMed] [Google Scholar]
  24. Sussman L. K., Robins L. N., Earls F. Treatment-seeking for depression by black and white Americans. Soc Sci Med. 1987;24(3):187–196. doi: 10.1016/0277-9536(87)90046-3. [DOI] [PubMed] [Google Scholar]
  25. Weintraub D., Raskin A., Ruskin P. E., Gruber-Baldini A. L., Zimmerman S. I., Hebel J. R., German P., Magaziner J. Racial differences in the prevalence of dementia among patients admitted to nursing homes. Psychiatr Serv. 2000 Oct;51(10):1259–1264. doi: 10.1176/appi.ps.51.10.1259. [DOI] [PubMed] [Google Scholar]
  26. Weintraub D., Raskin A., Ruskin P. E., Gruber-Baldini A. L., Zimmerman S. I., Hebel J. R., German P., Magaziner J. Racial differences in the prevalence of dementia among patients admitted to nursing homes. Psychiatr Serv. 2000 Oct;51(10):1259–1264. doi: 10.1176/appi.ps.51.10.1259. [DOI] [PubMed] [Google Scholar]

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